PDB entry 3q1e
View 3q1e on RCSB PDB site
Description: Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase in complex with T4
Class: hydrolase
Keywords: HIUASE, TRANSTHYRETIN, TRP, THYROID HORMONES, MOLECULAR EVOLUTION, PURINE METABOLISM, Greek key beta-barrel, Hydrolase, Point Mutation, peroxisome
Deposited on
2010-12-17, released
2011-05-04
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-01-01, with a file datestamp of
2019-12-27.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.32
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: 5-hydroxyisourate hydrolase
Species: Danio rerio [TaxId:7955]
Gene: urah
Database cross-references and differences (RAF-indexed):
- Uniprot Q06S87 (Start-118)
- engineered mutation (15)
- engineered mutation (115)
Domains in SCOPe 2.08: d3q1ea_ - Chain 'B':
Compound: 5-hydroxyisourate hydrolase
Species: Danio rerio [TaxId:7955]
Gene: urah
Database cross-references and differences (RAF-indexed):
- Uniprot Q06S87 (Start-118)
- engineered mutation (15)
- engineered mutation (115)
Domains in SCOPe 2.08: d3q1eb_ - Chain 'C':
Compound: 5-hydroxyisourate hydrolase
Species: Danio rerio [TaxId:7955]
Gene: urah
Database cross-references and differences (RAF-indexed):
- Uniprot Q06S87 (Start-118)
- engineered mutation (15)
- engineered mutation (115)
Domains in SCOPe 2.08: d3q1ec_ - Chain 'D':
Compound: 5-hydroxyisourate hydrolase
Species: Danio rerio [TaxId:7955]
Gene: urah
Database cross-references and differences (RAF-indexed):
- Uniprot Q06S87 (Start-118)
- engineered mutation (15)
- engineered mutation (115)
Domains in SCOPe 2.08: d3q1ed_ - Heterogens: T44, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3q1eA (A:)
msatllsplsthvlnaaqgvpganmtivlhrldpvssawnilttgitnddgrcpglitke
nfiagvykmrfetgkywdalgetcfypyveivftitntsqhyhvplllsrfsysttrgs
Sequence, based on observed residues (ATOM records): (download)
>3q1eA (A:)
splsthvlnaaqgvpganmtivlhrldpvssawnilttgitnddgrcpglitkenfiagv
ykmrfetgkywdalgetcfypyveivftitntsqhyhvplllsrfsysttrgs
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3q1eB (B:)
msatllsplsthvlnaaqgvpganmtivlhrldpvssawnilttgitnddgrcpglitke
nfiagvykmrfetgkywdalgetcfypyveivftitntsqhyhvplllsrfsysttrgs
Sequence, based on observed residues (ATOM records): (download)
>3q1eB (B:)
lsplsthvlnaaqgvpganmtivlhrldpvssawnilttgitnddgrcpglitkenfiag
vykmrfetgkywdalgetcfypyveivftitntsqhyhvplllsrfsysttrgs
- Chain 'C':
Sequence, based on SEQRES records: (download)
>3q1eC (C:)
msatllsplsthvlnaaqgvpganmtivlhrldpvssawnilttgitnddgrcpglitke
nfiagvykmrfetgkywdalgetcfypyveivftitntsqhyhvplllsrfsysttrgs
Sequence, based on observed residues (ATOM records): (download)
>3q1eC (C:)
lsplsthvlnaaqgvpganmtivlhrldpvssawnilttgitnddgrcpglitkenfiag
vykmrfetgkywdalgetcfypyveivftitntsqhyhvplllsrfsysttrgs
- Chain 'D':
Sequence, based on SEQRES records: (download)
>3q1eD (D:)
msatllsplsthvlnaaqgvpganmtivlhrldpvssawnilttgitnddgrcpglitke
nfiagvykmrfetgkywdalgetcfypyveivftitntsqhyhvplllsrfsysttrgs
Sequence, based on observed residues (ATOM records): (download)
>3q1eD (D:)
tllsplsthvlnaaqgvpganmtivlhrldpvssawnilttgitnddgrcpglitkenfi
agvykmrfetgkywdalgetcfypyveivftitntsqhyhvplllsrfsysttrgs