PDB entry 3pxy

View 3pxy on RCSB PDB site
Description: CDK2 in complex with inhibitor JWS648
Class: transferase/transferase inhibitor
Keywords: protein kinase, CDK2, inhibitor, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2010-12-10, released 2011-02-16
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-06-01, with a file datestamp of 2011-05-27.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.211
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3pxya_
  • Heterogens: JWS, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3pxyA (A:)
gplgspefmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstairei
sllkelnhpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqll
qglafchshrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrape
illgckyystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvts
mpdykpsfpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkp
vphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >3pxyA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirtegvpstaireisllkelnhpniv
klldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvl
hrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystav
diwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwa
rqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl