PDB entry 3pup

View 3pup on RCSB PDB site
Description: Structure of Glycogen Synthase Kinase 3 beta (GSK3B) in complex with a ruthenium octasporine ligand (OS1)
Class: transferase
Keywords: wnt signaling pathway, serine/threonine-protein kinase, ruthenium glycogen synthase kinase picomolar, nucleotide-binding, kinase, transferase, ATP-binding, phosphoprotein
Deposited on 2010-12-06, released 2010-12-22
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-02-29, with a file datestamp of 2012-02-24.
Experiment type: XRAY
Resolution: 2.99 Å
R-factor: 0.206
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycogen synthase kinase-3 beta
    Species: Homo sapiens [TaxId:9606]
    Gene: GSK3B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3pupa_
  • Chain 'B':
    Compound: Glycogen synthase kinase-3 beta
    Species: Homo sapiens [TaxId:9606]
    Gene: GSK3B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3pupb_
  • Heterogens: OS1

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3pupA (A:)
msgrprttsfaesckpvqqpsafgsmkvsrdkdgskvttvvatpgqgpdrpqevsytdtk
vigngsfgvvyqaklcdsgelvaikkvlqdkrfknrelqimrkldhcnivrlryffyssg
ekkdevylnlvldyvpetvyrvarhysrakqtlpviyvklymyqlfrslayihsfgichr
dikpqnllldpdtavlklcdfgsakqlvrgepnvsyicsryyrapelifgatdytssidv
wsagcvlaelllgqpifpgdsgvdqlveiikvlgtptreqiremnpnytefkfpqikahp
wtkvfrprtppeaialcsrlleytptarltpleacahsffdelrdpnvklpngrdtpalf
nfttqelssnpplatilipphariqaaastptnataasdantgdrgqtnnaasasasnst

    Sequence, based on observed residues (ATOM records): (download) 
    >3pupA (A:)
skvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfk
nrelqimrkldhcnivrlryffyssekkdevylnlvldyvpetvyrvarhysrakqtlpv
iyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnvs
yicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlgt
ptreqiremnpnytfkfpqikahpwtkvfrprtppeaialcsrlleytptarltpleaca
hsffdelrdpnvklpngrdtpalfnfttqelssnpplatilippha

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3pupB (B:)
msgrprttsfaesckpvqqpsafgsmkvsrdkdgskvttvvatpgqgpdrpqevsytdtk
vigngsfgvvyqaklcdsgelvaikkvlqdkrfknrelqimrkldhcnivrlryffyssg
ekkdevylnlvldyvpetvyrvarhysrakqtlpviyvklymyqlfrslayihsfgichr
dikpqnllldpdtavlklcdfgsakqlvrgepnvsyicsryyrapelifgatdytssidv
wsagcvlaelllgqpifpgdsgvdqlveiikvlgtptreqiremnpnytefkfpqikahp
wtkvfrprtppeaialcsrlleytptarltpleacahsffdelrdpnvklpngrdtpalf
nfttqelssnpplatilipphariqaaastptnataasdantgdrgqtnnaasasasnst

    Sequence, based on observed residues (ATOM records): (download) 
    >3pupB (B:)
skvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfk
nrelqimrkldhcnivrlryffyssekkdevylnlvldyvpetvyrvarhysrakqtlpv
iyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnvs
yicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlgt
ptreqiremnpnytfkfpqikahpwtkvfrprtppeaialcsrlleytptarltpleaca
hsffdelrdpnvklpngrdtpalfnfttqelssnpplatilipphar