PDB entry 3pui

View 3pui on RCSB PDB site
Description: Cocaine Esterase with mutations G4C, S10C
Class: hydrolase
Keywords: alpha/beta hydrolase, jelly-roll beta-barrel, Cleavage of cocaine, HYDROLASE
Deposited on 2010-12-04, released 2011-09-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 1.53 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cocaine esterase
    Species: Rhodococcus sp. [TaxId:104109]
    Gene: cocE
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9L9D7 (Start-573)
      • engineered mutation (3)
      • engineered mutation (9)
      • expression tag (574-575)
    Domains in SCOPe 2.08: d3puia1, d3puia2, d3puia3
  • Heterogens: CL, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3puiA (A:)
mvdcnysvacnvmvpmrdgvrlavdlyrpdadgpvpvllvrnpydkfdvfawstqstnwl
efvrdgyavviqdtrglfasegefvphvddeadaedtlswileqawcdgnvgmfgvsylg
vtqwqaavsgvgglkaiapsmasadlyrapwygpggalsveallgwsaligtglitsrsd
arpedaadfvqlaailndvagaasvtplaeqpllgrlipwvidqvvdhpdndeswqsisl
ferlgglatpalitagwydgfvgeslrtfvavkdnadarlvvgpwshsnltgrnadrkfg
iaatypiqeattmhkaffdrhlrgetdalagvpkvrlfvmgidewrdetdwplpdtaytp
fylggsgaantstgggtlstsisgtesadtylydpadpvpslggtllfhngdngpadqrp
ihdrddvlcystevltdpvevtgtvsarlfvsssavdtdftaklvdvfpdgraialcdgi
vrmryretlvnptlieageiyevaidmlatsnvflpghrimvqvsssnfpkydrnsntgg
viareqleemctavnrihrgpehpshivlpiikrklaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3puiA (A:)
dcnysvacnvmvpmrdgvrlavdlyrpdadgpvpvllvrnpydkfdvfawstqstnwlef
vrdgyavviqdtrglfasegefvphvddeadaedtlswileqawcdgnvgmfgvsylgvt
qwqaavsgvgglkaiapsmasadlyrapwygpggalsveallgwsaligtglitsrsdar
pedaadfvqlaailndvagaasvtplaeqpllgrlipwvidqvvdhpdndeswqsislfe
rlgglatpalitagwydgfvgeslrtfvavkdnadarlvvgpwshsnltgrnadrkfgia
atypiqeattmhkaffdrhlrgetdalagvpkvrlfvmgidewrdetdwplpdtaytpfy
lggsgaantstgggtlstsisgtesadtylydpadpvpslggtllfhngdngpadqrpih
drddvlcystevltdpvevtgtvsarlfvsssavdtdftaklvdvfpdgraialcdgivr
mryretlvnptlieageiyevaidmlatsnvflpghrimvqvsssnfpkydrnsntggvi
areqleemctavnrihrgpehpshivlpiikrkl