PDB entry 3pta

View 3pta on RCSB PDB site
Description: Crystal structure of human DNMT1(646-1600) in complex with DNA
Class: Transferase/DNA
Keywords: DNMT1, Maintenance DNA methylation, Transferase-DNA complex
Deposited on 2010-12-02, released 2010-12-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-03-30, with a file datestamp of 2011-03-25.
Experiment type: XRAY
Resolution: 3.6 Å
R-factor: 0.257
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA (cytosine-5)-methyltransferase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: DNMT1, AIM, CXXC9, DNMT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ptaa1, d3ptaa2, d3ptaa3, d3ptaa4, d3ptaa5
  • Chain 'B':
    Compound: DNA (5'-d(*tp*cp*cp*cp*gp*tp*gp*ap*gp*cp*cp*tp*cp*cp*gp*cp*ap*gp*g)-3')
  • Chain 'C':
    Compound: DNA (5'-d(*cp*cp*tp*gp*cp*gp*gp*ap*gp*gp*cp*tp*cp*ap*cp*gp*gp*gp*a)-3')
  • Heterogens: SAH, ZN

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ptaA (A:)
snafkrrrcgvcevcqqpecgkckackdmvkfggsgrskqacqerrcpnmamkeadddee
vddnipempspkkmhqgkkkkqnknriswvgeavktdgkksyykkvcidaetlevgdcvs
vipddsskplylarvtalwedssngqmfhahwfcagtdtvlgatsdplelflvdecedmq
lsyihskvkviykapsenwameggmdpesllegddgktyfyqlwydqdyarfesppktqp
tednkfkfcvscarlaemrqkeiprvleqledldsrvlyysatkngilyrvgdgvylppe
aftfniklsspvkrprkepvdedlypehyrkysdyikgsnldapepyrigrikeifcpkk
sngrpnetdikirvnkfyrpenthkstpasyhadinllywsdeeavvdfkavqgrctvey
gedlpecvqvysmggpnrfyfleaynaksksfedppnharspgnkgkgkgkgkgkpksqa
cepsepeieiklpklrtldvfsgcgglsegfhqagisdtlwaiemwdpaaqafrlnnpgs
tvftedcnillklvmagettnsrgqrlpqkgdvemlcggppcqgfsgmnrfnsrtyskfk
nslvvsflsycdyyrprffllenvrnfvsfkrsmvlkltlrclvrmgyqctfgvlqagqy
gvaqtrrraiilaaapgeklplfpeplhvfapracqlsvvvddkkfvsnitrlssgpfrt
itvrdtmsdlpevrngasaleisyngepqswfqrqlrgaqyqpilrdhickdmsalvaar
mrhiplapgsdwrdlpnievrlsdgtmarklrythhdrkngrsssgalrgvcscveagka
cdpaarqfntlipwclphtgnrhnhwaglygrlewdgffsttvtnpepmgkqgrvlhpeq
hrvvsvrecarsqgfpdtyrlfgnildkhrqvgnavppplakaigleiklcmlaka

    Sequence, based on observed residues (ATOM records): (download) 
    >3ptaA (A:)
afkrrrcgvcevcqqpecgkckackdmvkfggsgrskqacqerrcpnmamkeadddeevd
dnipempspkkmhqgkkkkqnknriswvgeavktdgkksyykkvcidaetlevgdcvsvi
pddsskplylarvtalwedssngqmfhahwfcagtdtvlgatsdplelflvdecedmqls
yihskvkviykapsenwameggmdpgktyfyqlwydqdyarfesppktqptednkfkfcv
scarlaemrqkeiprvleqledldsrvlyysatkngilyrvgdgvylppeaftfniklss
pkepvdedlypehyrkysnldapepyrigrikeifcpkksngrpnetdikirvnkfyrpe
nthkstpasyhadinllywsdeeavvdfkavqgrctveygedlpecvqvysmggpnrfyf
leaynaksksfedppnharspgklpklrtldvfsgcgglsegfhqagisdtlwaiemwdp
aaqafrlnnpgstvftedcnillklvmagettnsrgqrlpqkgdvemlcggppcqgfsgm
nrfnsrtyskfknslvvsflsycdyyrprffllenvrnfvsfkrsmvlkltlrclvrmgy
qctfgvlqagqygvaqtrrraiilaaapgeklplfpeplhvfapracqlsvvvddkkfvs
nitrlssgpfrtitvrdtmsdlpevrngasaleisyngepqswfqrqlrgaqyqpilrdh
ickdmsalvaarmrhiplapgsdwrdlpnievrlsdgtmarklrythhdrkngrsssgal
rgvcscvacdpaarqfntlipwclphtgnrhnhwaglygrlewdgffsttvtnpepmgkq
grvlhpeqhrvvsvrecarsqgfpdtyrlfgnildkhrqvgnavppplakaigleiklcm
laka

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.