PDB entry 3pt6

View 3pt6 on RCSB PDB site
Description: Crystal structure of mouse DNMT1(650-1602) in complex with DNA
Class: Transferase/DNA
Keywords: Maintenance DNA methylation, Transferase-DNA complex
Deposited on 2010-12-02, released 2010-12-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-03-30, with a file datestamp of 2011-03-25.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.213
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA (cytosine-5)-methyltransferase 1
    Species: Mus musculus [TaxId:10090]
    Gene: Dnmt1, Dnmt, Met1, Uim
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3pt6a1, d3pt6a2, d3pt6a3, d3pt6a4, d3pt6a5
  • Chain 'B':
    Compound: DNA (cytosine-5)-methyltransferase 1
    Species: Mus musculus [TaxId:10090]
    Gene: Dnmt1, Dnmt, Met1, Uim
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3pt6b1, d3pt6b2, d3pt6b3, d3pt6b4, d3pt6b5
  • Chain 'C':
    Compound: DNA (5'-d(*tp*cp*cp*cp*gp*tp*gp*ap*gp*cp*cp*tp*cp*cp*gp*cp*ap*gp*g)-3')
  • Chain 'D':
    Compound: DNA (5'-d(*tp*cp*cp*cp*gp*tp*gp*ap*gp*cp*cp*tp*cp*cp*gp*cp*ap*gp*g)-3')
  • Chain 'I':
    Compound: DNA (5'-d(*cp*cp*tp*gp*cp*gp*gp*ap*gp*gp*cp*tp*cp*ap*cp*gp*gp*gp*a)-3')
  • Chain 'J':
    Compound: DNA (5'-d(*cp*cp*tp*gp*cp*gp*gp*ap*gp*gp*cp*tp*cp*ap*cp*gp*gp*gp*a)-3')
  • Heterogens: SAH, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3pt6A (A:)
samkrrrcgvcevcqqpecgkckackdmvkfggtgrskqaclkrrcpnlavkeadddeea
dddvsempspkklhqgkkkkqnkdriswlgqpmkieenrtyyqkvsideemlevgdcvsv
ipddsskplylarvtalwedkngqmmfhahwfcagtdtvlgatsdplelflvgecenmql
syihskvkviykapsenwameggtdpettlpgaedgktyffqlwynqeyarfesppktqp
tednkhkfclscirlaelrqkempkvleqieevdgrvycssitkngvvyrlgdsvylppe
aftfnikvaspvkrpkkdpvnetlypehyrkysdyikgsnldapepyrigrikeihcgkk
kgkvneadiklrlykfyrpenthrsyngsyhtdinmlywsdeeavvnfsdvqgrctveyg
edllesiqdysqggpdrfyfleaynsktknfedppnharspgnkgkgkgkgkgkgkhqvs
epkepeaaiklpklrtldvfsgcgglsegfhqagisetlwaiemwdpaaqafrlnnpgtt
vftedcnvllklvmagevtnslgqrlpqkgdvemlcggppcqgfsgmnrfnsrtyskfkn
slvvsflsycdyyrprffllenvrnfvsyrrsmvlkltlrclvrmgyqctfgvlqagqyg
vaqtrrraiilaaapgeklplfpeplhvfapracqlsvvvddkkfvsnitrlssgpfrti
tvrdtmsdlpeiqngasnseipyngeplswfqrqlrgshyqpilrdhickdmsplvaarm
rhiplfpgsdwrdlpniqvrlgdgviahklqytfhdvkngysstgalrgvcscaegkacd
pesrqfstlipwclphtgnrhnhwaglygrlewdgffsttvtnpepmgkqgrvlhpeqhr
vvsvrecarsqgfpdsyrffgnildrhrqvgnavppplakaigleiklcllssa

    Sequence, based on observed residues (ATOM records): (download) 
    >3pt6A (A:)
mkrrrcgvcevcqqpecgkckackdmvkfggtgrskqaclkrrcpnlavkeadddeeadd
dvsempspkklhqgkkkkqnkdriswlgqpmkieenrtyyqkvsideemlevgdcvsvip
ddsskplylarvtalwedkngqmmfhahwfcagtdtvlgatsdplelflvgecenmqlsy
ihskvkviykapsenwameggktyffqlwynqeyarfesppktqptednkhkfclscirl
aelrqkempkvleqieevdgrvycssitkngvvyrlgdsvylppeaftfnikvaspvkrp
kkdpvnetlypehyrkysdyikgsnldapepyrigrikeihcgkkkgkvneadiklrlyk
fyrpenthrsyngsyhtdinmlywsdeeavvnfsdvqgrctveygedllesiqdysqggp
drfyfleaynsktknfedppnharspgnkgkglpklrtldvfsgcgglsegfhqagiset
lwaiemwdpaaqafrlnnpgttvftedcnvllklvmagevtnslgqrlpqkgdvemlcgg
ppcqgfsgmnrfnsrtyskfknslvvsflsycdyyrprffllenvrnfvsyrrsmvlklt
lrclvrmgyqctfgvlqagqygvaqtrrraiilaaapgeklplfpeplhvfapracqlsv
vvddkkfvsnitrlssgpfrtitvrdtmsdlpeiqngasnseipyngeplswfqrqlrgs
hyqpilrdhickdmsplvaarmrhiplfpgsdwrdlpniqvrlgdgviahklqytfhdvk
ngysstgalrgvcscaegkacdpesrqfstlipwclphtgnrhnhwaglygrlewdgffs
ttvtnpepmgkqgrvlhpeqhrvvsvrecarsqgfpdsyrffgnildrhrqvgnavpppl
akaigleiklclls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3pt6B (B:)
samkrrrcgvcevcqqpecgkckackdmvkfggtgrskqaclkrrcpnlavkeadddeea
dddvsempspkklhqgkkkkqnkdriswlgqpmkieenrtyyqkvsideemlevgdcvsv
ipddsskplylarvtalwedkngqmmfhahwfcagtdtvlgatsdplelflvgecenmql
syihskvkviykapsenwameggtdpettlpgaedgktyffqlwynqeyarfesppktqp
tednkhkfclscirlaelrqkempkvleqieevdgrvycssitkngvvyrlgdsvylppe
aftfnikvaspvkrpkkdpvnetlypehyrkysdyikgsnldapepyrigrikeihcgkk
kgkvneadiklrlykfyrpenthrsyngsyhtdinmlywsdeeavvnfsdvqgrctveyg
edllesiqdysqggpdrfyfleaynsktknfedppnharspgnkgkgkgkgkgkgkhqvs
epkepeaaiklpklrtldvfsgcgglsegfhqagisetlwaiemwdpaaqafrlnnpgtt
vftedcnvllklvmagevtnslgqrlpqkgdvemlcggppcqgfsgmnrfnsrtyskfkn
slvvsflsycdyyrprffllenvrnfvsyrrsmvlkltlrclvrmgyqctfgvlqagqyg
vaqtrrraiilaaapgeklplfpeplhvfapracqlsvvvddkkfvsnitrlssgpfrti
tvrdtmsdlpeiqngasnseipyngeplswfqrqlrgshyqpilrdhickdmsplvaarm
rhiplfpgsdwrdlpniqvrlgdgviahklqytfhdvkngysstgalrgvcscaegkacd
pesrqfstlipwclphtgnrhnhwaglygrlewdgffsttvtnpepmgkqgrvlhpeqhr
vvsvrecarsqgfpdsyrffgnildrhrqvgnavppplakaigleiklcllssa

    Sequence, based on observed residues (ATOM records): (download) 
    >3pt6B (B:)
amkrrrcgvcevcqqpecgkckackdmvkfggtgrskqaclkrrcpnlavkeadddeead
ddvsempspkklhqgkkkkqnkdriswlgqpmkieenrtyyqkvsideemlevgdcvsvi
pddsskplylarvtalwedkngqmmfhahwfcagtdtvlgatsdplelflvgecenmqls
yihskvkviykapsenwameggdgktyffqlwynqeyarfesppktqptednkhkfclsc
irlaelrqkempkvleqieevdgrvycssitkngvvyrlgdsvylppeaftfnikvaspv
krpkkdpvnetlypehyrkysdyikgsnldapepyrigrikeihcgkkkgkvneadiklr
lykfyrpenthrsyngsyhtdinmlywsdeeavvnfsdvqgrctveygedllesiqdysq
ggpdrfyfleaynsktknfedppnharspgnkklpklrtldvfsgcgglsegfhqagise
tlwaiemwdpaaqafrlnnpgttvftedcnvllklvmagevtnslgqrlpqkgdvemlcg
gppcqgfsgmnrfnsrtyskfknslvvsflsycdyyrprffllenvrnfvsyrrsmvlkl
tlrclvrmgyqctfgvlqagqygvaqtrrraiilaaapgeklplfpeplhvfapracqls
vvvddkkfvsnitrlssgpfrtitvrdtmsdlpeiqngasnseipyngeplswfqrqlrg
shyqpilrdhickdmsplvaarmrhiplfpgsdwrdlpniqvrlgdgviahklqytfhdv
kngysstgalrgvcscaegkacdpesrqfstlipwclphtgnrhnhwaglygrlewdgff
sttvtnpepmgkqgrvlhpeqhrvvsvrecarsqgfpdsyrffgnildrhrqvgnavppp
lakaigleiklclls

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    No sequence available.