PDB entry 3ppx
View 3ppx on RCSB PDB site
Description: Crystal structure of the N1602A mutant of an engineered VWF A2 domain (N1493C and C1670S)
Class: cell adhesion
Keywords: von Willebrand factor, VWA domain, Rossmann fold, blood coagulation, cell adhesion, protein unfolding, ADAMTS13 cleavage, glycosylation
Deposited on
2010-11-25, released
2011-05-04
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-11-08, with a file datestamp of
2017-11-03.
Experiment type: XRAY
Resolution: 1.91 Å
R-factor: N/A
AEROSPACI score: 0.34
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: von willebrand factor
Species: Homo sapiens [TaxId:9606]
Gene: F8VWF, VWF
Database cross-references and differences (RAF-indexed):
- Uniprot P04275 (Start-187)
- engineered mutation (6)
- engineered mutation (115)
- engineered mutation (183)
- expression tag (188-189)
Domains in SCOPe 2.08: d3ppxa1, d3ppxa2 - Heterogens: NA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3ppxA (A:)
mlgpkrcsmvldvafvlegsdkigeadfnrskefmeeviqrmdvgqdsihvtvlqysymv
tveypfseaqskgdilqrvreiryqggnrtntglalrylsdhsflvsqgdreqapalvym
vtgnpasdeikrlpgdiqvvpigvgpnanvqelerigwpnapiliqdfetlpreapdlvl
qrcssgeglehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>3ppxA (A:)
csmvldvafvlegsdkigeadfnrskefmeeviqrmdvgqdsihvtvlqysymvtveypf
seaqskgdilqrvreiryqggnrtntglalrylsdhsflvsqgdreqapalvymvtgnpa
sdeikrlpgdiqvvpigvgpnanvqelerigwpnapiliqdfetlpreapdlvlqrcssg
egle