PDB entry 3ppx

View 3ppx on RCSB PDB site
Description: Crystal structure of the N1602A mutant of an engineered VWF A2 domain (N1493C and C1670S)
Class: cell adhesion
Keywords: von Willebrand factor, VWA domain, Rossmann fold, blood coagulation, cell adhesion, protein unfolding, ADAMTS13 cleavage, glycosylation
Deposited on 2010-11-25, released 2011-05-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 1.91 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: von willebrand factor
    Species: Homo sapiens [TaxId:9606]
    Gene: F8VWF, VWF
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04275 (Start-187)
      • engineered mutation (6)
      • engineered mutation (115)
      • engineered mutation (183)
      • expression tag (188-189)
    Domains in SCOPe 2.08: d3ppxa1, d3ppxa2
  • Heterogens: NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3ppxA (A:)
    mlgpkrcsmvldvafvlegsdkigeadfnrskefmeeviqrmdvgqdsihvtvlqysymv
    tveypfseaqskgdilqrvreiryqggnrtntglalrylsdhsflvsqgdreqapalvym
    vtgnpasdeikrlpgdiqvvpigvgpnanvqelerigwpnapiliqdfetlpreapdlvl
    qrcssgeglehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >3ppxA (A:)
    csmvldvafvlegsdkigeadfnrskefmeeviqrmdvgqdsihvtvlqysymvtveypf
    seaqskgdilqrvreiryqggnrtntglalrylsdhsflvsqgdreqapalvymvtgnpa
    sdeikrlpgdiqvvpigvgpnanvqelerigwpnapiliqdfetlpreapdlvlqrcssg
    egle