PDB entry 3poo

View 3poo on RCSB PDB site
Description: human cAMP-dependent protein kinase in complex with an inhibitor
Class: transferase/transferase inhibitor
Keywords: ATP Binding, Phosphorylation, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2010-11-23, released 2011-11-16
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-11-16, with a file datestamp of 2011-11-11.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.187
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cAMP-dependent protein kinase catalytic subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: Pkaca, Prkaca
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3pooa_
  • Chain 'B':
    Compound: cAMP-dependent protein kinase inhibitor alpha
    Database cross-references and differences (RAF-indexed):
  • Heterogens: S69, BUD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3pooA (A:)
mgnaaaakkgseqesvkeflakakedflkkwespaqntahldqferiktlgtgsfgrvml
vkhketgnhyamkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymv
meyvpggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgy
iqvtdfgfakrvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppff
adqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfat
tdwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsinekcgkefsef

    Sequence, based on observed residues (ATOM records): (download) 
    >3pooA (A:)
svkeflakakedflkkwespaqntahldqferiktlgtgsfgrvmlvkhketgnhyamki
ldkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvpggemfshlr
rigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfakrvkg
rtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekivsg
kvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkveap
fipkfdtsnfddyeeeeirvsinekcgkefsef

  • Chain 'B':
    No sequence available.