PDB entry 3pj8
View 3pj8 on RCSB PDB site
Description: Structure of CDK2 in complex with a Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine.
Class: transferase/transferase inhibitor
Keywords: PHOSPHORYLATION, CELL DIVISION, MITOSIS, Cyclin, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on
2010-11-09, released
2011-04-06
The last revision prior to the SCOPe 2.08 freeze date was dated
2011-05-11, with a file datestamp of
2011-05-06.
Experiment type: XRAY
Resolution: 1.96 Å
R-factor: 0.206
AEROSPACI score: 0.43
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cell division protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: CDK2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3pj8a1, d3pj8a2 - Heterogens: 404, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3pj8A (A:)
gmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps
fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
Sequence, based on observed residues (ATOM records): (download)
>3pj8A (A:)
gmenfqkvekigegtygvvykarnkltgevvalkkiretegvpstaireisllkelnhpn
ivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshr
vlhrdlkpqnllintegaikladfglarafgvvvtlwyrapeillgckyystavdiwslg
cifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfsk
vvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl