PDB entry 3piy
View 3piy on RCSB PDB site
Description: Crystal structure of BTK kinase domain complexed with R406
Class: transferase/inhibitor
Keywords: helix C-out, DFG-in, TRANSFERASE, TRANSFERASE-INHIBITOR complex
Deposited on
2010-11-08, released
2011-01-12
The last revision prior to the SCOPe 2.05 freeze date was dated
2011-04-27, with a file datestamp of
2011-04-22.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: 0.228
AEROSPACI score: 0.29
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Tyrosine-protein kinase BTK
Species: Homo sapiens [TaxId:9606]
Gene: AGMX1, ATK, BPK, BTK
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d3piya_ - Heterogens: 585, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3piyA (A:)
gtaglgygsweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefiee
akvmmnlsheklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdv
ceameyleskqflhrdlaarnclvndqgvvkvsdfglsryvlddeytssvgskfpvrwsp
pevlmyskfssksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlasek
vytimyscwhekaderptfkillsnildvmdees
Sequence, based on observed residues (ATOM records): (download)
>3piyA (A:)
gygsweidpkdltflkelgtgqfgvvkygkwrgqydvaikmiedefieeakvmmnlshek
lvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceameyleskq
flhrdlaarnclvndqgvvkvsdfglsryvlddeytssvgskfpvrwsppevlmyskfss
ksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvytimyscwhe
kaderptfkillsnildvmdee