PDB entry 3pd1

View 3pd1 on RCSB PDB site
Description: Caspase-3 K242A
Class: hydrolase/hydrolase inhibitor
Keywords: Salt Bridge, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2010-10-22, released 2011-02-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-11-16, with a file datestamp of 2011-11-11.
Experiment type: XRAY
Resolution: 1.62 Å
R-factor: 0.208
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Caspase-3
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP3, CPP32
    Database cross-references and differences (RAF-indexed):
    • Uniprot P42574 (Start-248)
      • engineered mutation (213)
      • expression tag (249)
    Domains in SCOPe 2.08: d3pd1a1, d3pd1a2
  • Chain 'B':
    Compound: inhibitor ac-devd-cmk
    Database cross-references and differences (RAF-indexed):
    • PDB 3PD1 (Start-4)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3pd1A (A:)
sgisldnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnk
ndltreeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrc
rsltgkpklfiiqacrgteldcgietdsgvdddmachkipveadflyaystapgyyswrn
skdgswfiqslcamlkqyadklefmhiltrvnravatefesfsfdatfhakkqipcivsm
ltkelyfyhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3pd1A (A:)
gisldnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnkn
dltreeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrcr
sltgkpklfiiqacrgteldcgiehkipveadflyaystapgyyswrnskdgswfiqslc
amlkqyadklefmhiltrvnravatefesfsfdatfhakkqipcivsmltkelyfyhh

  • Chain 'B':
    No sequence available.