PDB entry 3pcu

View 3pcu on RCSB PDB site
Description: Crystal structure of human retinoic X receptor alpha ligand-binding domain complexed with LX0278 and SRC1 peptide
Class: transcription/transcription regulator
Keywords: nuclear receptor RXRalpha, ligand-binding domain, TRANSCRIPTION-TRANSCRIPTION REGULATOR complex
Deposited on 2010-10-22, released 2011-11-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-04-11, with a file datestamp of 2012-04-06.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.201
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Retinoic acid receptor RXR-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: RXRA, NR2B1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3pcua_
  • Chain 'B':
    Compound: nuclear receptor coactivator 2
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: LX8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3pcuA (A:)
dmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvewakriph
fselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaifdr
vltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckhky
peqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleap

    Sequence, based on observed residues (ATOM records): (download) 
    >3pcuA (A:)
dmpverileaelavedpvtnicqaadkqlftlvewakriphfselplddqvillragwne
lliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdktel
gclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalrs
iglkclehlfffkligdtpidtflmemleap

  • Chain 'B':
    No sequence available.