PDB entry 3pcu
View 3pcu on RCSB PDB site
Description: Crystal structure of human retinoic X receptor alpha ligand-binding domain complexed with LX0278 and SRC1 peptide
Class: transcription/transcription regulator
Keywords: nuclear receptor RXRalpha, ligand-binding domain, TRANSCRIPTION-TRANSCRIPTION REGULATOR complex
Deposited on
2010-10-22, released
2011-11-16
The last revision prior to the SCOPe 2.08 freeze date was dated
2012-04-11, with a file datestamp of
2012-04-06.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.201
AEROSPACI score: 0.45
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Retinoic acid receptor RXR-alpha
Species: Homo sapiens [TaxId:9606]
Gene: RXRA, NR2B1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3pcua_ - Chain 'B':
Compound: nuclear receptor coactivator 2
Species: HOMO SAPIENS, synthetic [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Heterogens: LX8, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3pcuA (A:)
dmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvewakriph
fselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaifdr
vltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckhky
peqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleap
Sequence, based on observed residues (ATOM records): (download)
>3pcuA (A:)
dmpverileaelavedpvtnicqaadkqlftlvewakriphfselplddqvillragwne
lliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdktel
gclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalrs
iglkclehlfffkligdtpidtflmemleap
- Chain 'B':
No sequence available.