PDB entry 3pae

View 3pae on RCSB PDB site
Description: Crystal structure of the K84D mutant of OXA-24/40 in complex with doripenem
Class: hydrolase/antibiotic
Keywords: hydrolase, carbapenemase, HYDROLASE-ANTIBIOTIC complex
Deposited on 2010-10-19, released 2011-01-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-10-05, with a file datestamp of 2016-09-30.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: ACINETOBACTER BAUMANNII [TaxId:470]
    Gene: blaOXA-33, bla-OXA-40, blaOXA-24, blaOXA-40, oxa-24, oxa40
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8RLA6 (1-244)
      • engineered mutation (53)
    Domains in SCOPe 2.08: d3paea_
  • Chain 'B':
    Compound: Beta-lactamase
    Species: ACINETOBACTER BAUMANNII [TaxId:470]
    Gene: blaOXA-33, bla-OXA-40, blaOXA-24, blaOXA-40, oxa-24, oxa40
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8RLA6 (1-244)
      • engineered mutation (53)
    Domains in SCOPe 2.08: d3paeb_
  • Heterogens: 4J6, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3paeA (A:)
mhissqqhekaiksyfdeaqtqgviiikegknlstygnalarankeyvpastfdmlnali
glenhkattneifkwdgkkrtypmwekdmtlgeamalsavpvyqelarrtglelmqkevk
rvnfgntnigtqvdnfwlvgplkitpvqevnfaddlahnrlpfkletqeevkkmllikev
ngskiyaksgwgmgvtpqvgwltgwveqangkkipfslnlemkegmsgsirneityksle
nlgii

    Sequence, based on observed residues (ATOM records): (download) 
    >3paeA (A:)
hissqqhekaiksyfdeaqtqgviiikegknlstygnalarankeyvpastfdmlnalig
lenhkattneifkwdgkkrtypmwekdmtlgeamalsavpvyqelarrtglelmqkevkr
vnfgntnigtqvdnfwlvgplkitpvqevnfaddlahnrlpfkletqeevkkmllikevn
gskiyaksgwgmgvtpqvgwltgwveqangkkipfslnlemkegmsgsirneitykslen
lgii

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3paeB (B:)
mhissqqhekaiksyfdeaqtqgviiikegknlstygnalarankeyvpastfdmlnali
glenhkattneifkwdgkkrtypmwekdmtlgeamalsavpvyqelarrtglelmqkevk
rvnfgntnigtqvdnfwlvgplkitpvqevnfaddlahnrlpfkletqeevkkmllikev
ngskiyaksgwgmgvtpqvgwltgwveqangkkipfslnlemkegmsgsirneityksle
nlgii

    Sequence, based on observed residues (ATOM records): (download) 
    >3paeB (B:)
hissqqhekaiksyfdeaqtqgviiikegknlstygnalarankeyvpastfdmlnalig
lenhkattneifkwdgkkrtypmwekdmtlgeamalsavpvyqelarrtglelmqkevkr
vnfgntnigtqvdnfwlvgplkitpvqevnfaddlahnrlpfkletqeevkkmllikevn
gskiyaksgwgmgvtpqvgwltgwveqangkkipfslnlemkegmsgsirneitykslen
lgii