PDB entry 3p92

View 3p92 on RCSB PDB site
Description: Human mesotrypsin complexed with bovine pancreatic trypsin inhibitor variant (BPTI-K15R/R17G)
Class: hydrolase/hydrolase inhibitor
Keywords: mesotrypsin, trypsin IV, canonical inhibitor, bovine pancreatic trypsin inibitor, BPTI, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2010-10-15, released 2011-08-31
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-11-09, with a file datestamp of 2011-11-04.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.115
AEROSPACI score: 0.66 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: PRSS3 protein
  Species: Homo sapiens [TaxId:9606]
  Gene: PRSS3
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q8N2U3 (0-223)
    • engineered mutation (176)
  Domains in SCOPe 2.02: d3p92a_
• Chain 'E':
  Compound: pancreatic trypsin inhibitor
  Species: Bos taurus [TaxId:9913]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00974 (0-57)
    • engineered mutation (14)
    • engineered mutation (16)
  Domains in SCOPe 2.02: d3p92e_
• Heterogens: CA, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3p92A (A:)
  ivggytceenslpyqvslnsgshfcggsliseqwvvsaahcyktriqvrlgehnikvleg
  neqfinaakiirhpkynrdtldndimliklsspavinarvstislptappaagteclisg
  wgntlsfgadypdelkcldapvltqaeckasypgkitnsmfcvgfleggkdscqrdaggp
  vvcngqlqgvvswghgcawknrpgvytkvynyvdwikdtiaans
  

  
  
• Chain 'E':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3p92E (E:)
  rpdfcleppytgpcragiiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga