PDB entry 3p8w

View 3p8w on RCSB PDB site
Description: Crystal Structure Analysis of R29M/E81M double mutant of human CLIC1
Class: transport protein
Keywords: CLIC; Glutathione Transferase, thioredoxin, salt bridge, ion channel, TRANSPORT PROTEIN
Deposited on 2010-10-15, released 2010-11-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2010-11-03, with a file datestamp of 2010-10-29.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.214
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: chloride intracellular channel protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CLIC1, G6, NCC27
    Database cross-references and differences (RAF-indexed):
    • Uniprot O00299 (Start-240)
      • engineered mutation (28)
      • engineered mutation (80)
    Domains in SCOPe 2.07: d3p8wa1, d3p8wa2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3p8wA (A:)
    maeeqpqvelfvkagsdgakigncpfsqmlfmvlwlkgvtfnvttvdtkrrtetvqklcp
    ggqlpfllygtevhtdtnkimefleavlcpprypklaalnpesntagldifakfsayikn
    snpalndnlekgllkalkvldnyltsplpeevdetsaedegvsqrkfldgneltladcnl
    lpklhivqvvckkyrgftipeafrgvhrylsnayareefastcpddeeielayeqvakal
    k
    

    Sequence, based on observed residues (ATOM records): (download)
    >3p8wA (A:)
    pqvelfvkagsdgakigncpfsqmlfmvlwlkgvtfnvttvdtkrrtetvqklcpggqlp
    fllygtevhtdtnkimefleavlcpprypklaalnpesntagldifakfsayiknsnpal
    ndnlekgllkalkvldnyltsplpeevdetsaedegvsqrkfldgneltladcnllpklh
    ivqvvckkyrgftipeafrgvhrylsnayareefastcpddeeielayeqvakalk