PDB entry 3p5z
View 3p5z on RCSB PDB site
Description: Crystal structure of the mutant T159S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
Class: lyase
Keywords: tim barrel, orotidine 5'-monophosphate decarboxylase, inhibitor BMP, LYASE
Deposited on
2010-10-11, released
2011-09-21
The last revision prior to the SCOPe 2.02 freeze date was dated
2011-09-21, with a file datestamp of
2011-09-16.
Experiment type: XRAY
Resolution: 1.3 Å
R-factor: 0.165
AEROSPACI score: 0.76
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: orotidine 5'-monophosphate decarboxylase
Species: Methanobacterium thermoautotrophicum [TaxId:187420]
Gene: pyrF, MTH_129
Database cross-references and differences (RAF-indexed):
- Uniprot O26232
- conflict (100)
- engineered mutation (158)
- Chain 'B':
Compound: orotidine 5'-monophosphate decarboxylase
Species: Methanobacterium thermoautotrophicum [TaxId:187420]
Gene: pyrF, MTH_129
Database cross-references and differences (RAF-indexed):
- Uniprot O26232
- conflict (100)
- engineered mutation (158)
Domains in SCOPe 2.02: d3p5zb_ - Heterogens: BMP, GOL, POL, HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3p5zB (B:)
mrsrrvdvmdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefr
krfgcriiadfkvadipetnekicratfkagadaiivhgfpgadsvraclnvaeemgrev
flltemshpgaemfiqgaadeiarmgvdlgvknyvgpssrperlsrlreiigqdsflisp
gvgaqggdpgetlrfadaiivgrsiyladnpaaaaagiiesikdllnp
Sequence, based on observed residues (ATOM records): (download)
>3p5zB (B:)
dvmdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefrkrfgcr
iiadfkvadipetnekicratfkagadaiivhgfpgadsvraclnvaeemgrevflltem
shpgaemfiqgaadeiarmgvdlgvknyvgpssrperlsrlreiigqdsflispgvgaqg
gdpgetlrfadaiivgrsiyladnpaaaaagiiesikdll