PDB entry 3p0v

View 3p0v on RCSB PDB site
Description: anti-EGFR/HER3 Fab DL11 alone
Class: immune system
Keywords: beta-sandwich, immune system, antigens EGFR and HER3
Deposited on 2010-09-29, released 2011-10-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-03-21, with a file datestamp of 2012-03-16.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: 0.23
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Fab DL11 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3P0V (0-End)
    Domains in SCOPe 2.08: d3p0vh_
  • Chain 'I':
    Compound: Fab DL11 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3P0V (0-End)
    Domains in SCOPe 2.08: d3p0vi_
  • Chain 'L':
    Compound: Fab DL11 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3P0V (0-End)
    Domains in SCOPe 2.08: d3p0vl1, d3p0vl2
  • Chain 'M':
    Compound: Fab DL11 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3P0V (0-End)
    Domains in SCOPe 2.08: d3p0vm1, d3p0vm2
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >3p0vH (H:)
evqlvesggglvqpggslrlscaasgftlsgdwihwvrqapgkglewlgeisaaggytdy
adsvkgrftisadtskntaylqmnslraedtavyycaresrvsfeaamdywgqgtlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >3p0vH (H:)
evqlvesggglvqpggslrlscaasgftlsgdwihwvrqapgkglewlgeisaaggytdy
adsvkgrftisadtskntaylqmnslraedtavyycaresrvsfeaamdywgqgtlvtvs
sastkgpsvfplapssgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglys
lssvvtvpssslgtqtyicnvnhkpsntkvdkkvepks

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >3p0vI (I:)
evqlvesggglvqpggslrlscaasgftlsgdwihwvrqapgkglewlgeisaaggytdy
adsvkgrftisadtskntaylqmnslraedtavyycaresrvsfeaamdywgqgtlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >3p0vI (I:)
evqlvesggglvqpggslrlscaasgftlsgdwihwvrqapgkglewlgeisaaggytdy
adsvkgrftisadtskntaylqmnslraedtavyycaresrvsfeaamdywgqgtlvtvs
sastkgpsvfplapssksgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >3p0vL (L:)
diqmtqspsslsasvgdrvtitcrasqdlatdvawyqqkpgkapklliysasflysgvps
rfsgsgsgtdftltisslqpedfatyycqqsepepytfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >3p0vL (L:)
diqmtqspsslsasvgdrvtitcrasqdlatdvawyqqkpgkapklliysasflysgvps
rfsgsgsgtdftltisslqpedfatyycqqsepepytfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrg

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >3p0vM (M:)
diqmtqspsslsasvgdrvtitcrasqdlatdvawyqqkpgkapklliysasflysgvps
rfsgsgsgtdftltisslqpedfatyycqqsepepytfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >3p0vM (M:)
diqmtqspsslsasvgdrvtitcrasqdlatdvawyqqkpgkapklliysasflysgvps
rfsgsgsgtdftltisslqpedfatyycqqsepepytfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrg