PDB entry 3oy1

View 3oy1 on RCSB PDB site
Description: Highly Selective c-Jun N-Terminal Kinase (JNK) 2 and 3 Inhibitors with In Vitro CNS-like Pharmacokinetic Properties
Class: transherase/transferase inhibitor
Keywords: Kinase inhibitor, CNS, Selectivity, TRANSFERASE, transherase-transferase inhibitor complex
Deposited on 2010-09-22, released 2011-08-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-08-17, with a file datestamp of 2011-08-12.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.259
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 10
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK10, JNK3, JNK3A, PRKM10
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3oy1a_
  • Heterogens: 589, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3oy1A (A:)
skskvdnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpf
qnqthakrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqm
eldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagtsfm
mtpyvvtryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieql
gtpcpefmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllskm
lvidpakrisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliykevm
ns

    Sequence, based on observed residues (ATOM records): (download) 
    >3oy1A (A:)
nqfysvevgdstftvlkryqnlkpigsgivcaaydavldrnvaikklsrpfqnqthakra
yrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldhermsy
llyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglvtryyrapevilgmgyke
nvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpefmkklqptvrnyvenrp
kyagltfpklfpdslfpadsehnklkasqardllskmlvidpakrisvddalqhpyinvw
ydpaeveapperehtieewkeliykevmn