PDB entry 3oxz
View 3oxz on RCSB PDB site
Description: Crystal structure of ABL kinase domain bound with a DFG-out inhibitor AP24534
Class: transferase/transferase inhibitor
Keywords: protein-inhibitor complex, protein kinase two-domain fold, phosphotransferase, ATP binding, phosphorylation, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on
2010-09-22, released
2010-12-15
The last revision prior to the SCOPe 2.03 freeze date was dated
2010-12-22, with a file datestamp of
2010-12-17.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.218
AEROSPACI score: 0.38
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Tyrosine-protein kinase ABL1
Species: Mus musculus [TaxId:10090]
Gene: Abl1, Abl
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3oxza_ - Heterogens: 0LI, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3oxzA (A:)
gspnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveeflkea
avmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvllymatqi
ssameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwta
peslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpek
vyelmracwqwnpsdrpsfaeihqafetmfqessisdevekelg
Sequence, based on observed residues (ATOM records): (download)
>3oxzA (A:)
gspnydkwemertditmkhklgggqygevyegvwkkysltvavktlveeflkeaavmkei
khpnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvllymatqissamey
lekknfihrdlaarnclvgenhlvkvadfglsytgakfpikwtapeslaynkfsiksdvw
afgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyelmracwqwnpsdr
psfaeihqafetmfqessisdevekelg