PDB entry 3omp

View 3omp on RCSB PDB site
Description: Fragment-Based Design of novel Estrogen Receptor Ligands
Class: protein binding
Keywords: Steroid binding, PROTEIN BINDING
Deposited on 2010-08-27, released 2011-03-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-04-20, with a file datestamp of 2011-04-15.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.201
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Estrogen receptor beta
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR2, ESTRB, NR3A2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ompa_
  • Chain 'B':
    Compound: Estrogen receptor beta
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR2, ESTRB, NR3A2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ompb_
  • Chain 'C':
    Compound: Nuclear receptor coactivator 1
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Nuclear receptor coactivator 1
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Heterogens: W14, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ompA (A:)
dalspeqlvltlleaepphvlisrpsapfteasmmmsltkladkelvhmiswakkipgfv
elslfdqvrllescwmevlmmglmwrsidhpgklifapdlvldrdegkcvegileifdml
lattsrfrelklqhkeylcvkamillnssmyplvtatqdadssrklahllnavtdalvwv
iaksgissqqqsmrlanllmllshvrhasnkgmehllnmkcknvvpvydlllemlnahvl

    Sequence, based on observed residues (ATOM records): (download) 
    >3ompA (A:)
speqlvltlleaepphvlisrpsapfteasmmmsltkladkelvhmiswakkipgfvels
lfdqvrllescwmevlmmglmwrsidhpgklifapdlvldrdegkcvegileifdmllat
tsrfrelklqhkeylcvkamillnssmyplvtdssrklahllnavtdalvwviaksgiss
qqqsmrlanllmllshvrhasnkgmehllnmkcknvvpvydlllemlna

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3ompB (B:)
dalspeqlvltlleaepphvlisrpsapfteasmmmsltkladkelvhmiswakkipgfv
elslfdqvrllescwmevlmmglmwrsidhpgklifapdlvldrdegkcvegileifdml
lattsrfrelklqhkeylcvkamillnssmyplvtatqdadssrklahllnavtdalvwv
iaksgissqqqsmrlanllmllshvrhasnkgmehllnmkcknvvpvydlllemlnahvl

    Sequence, based on observed residues (ATOM records): (download) 
    >3ompB (B:)
speqlvltlleaepphvlisrpsapfteasmmmsltkladkelvhmiswakkipgfvels
lfdqvrllescwmevlmmglmwrsidhpgklifapdlvldrdegkcvegileifdmllat
tsrfrelklqhkeylcvkamillnssmyplvtaklahllnavtdalvwviaksgissqqq
smrlanllmllshvrhasnkgmehllnmkcknvvpvydllleml

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.