PDB entry 3oap

View 3oap on RCSB PDB site
Description: Crystal structure of human Retinoid X Receptor alpha-ligand binding domain complex with 9-cis retinoic acid and the coactivator peptide GRIP-1
Class: transcription
Keywords: antiparallel sandwich, ligand binding, coactivator binding, dimerization, activation function, TRANSCRIPTION
Deposited on 2010-08-05, released 2010-11-17
The last revision prior to the SCOPe 2.01 freeze date was dated 2010-11-17, with a file datestamp of 2010-11-12.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.204
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Retinoic acid receptor RXR-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: RXRA, NR2B1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3oapa_
  • Chain 'B':
    Compound: nuclear receptor coactivator 2
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: REA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3oapA (A:)
edmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvewakrip
hfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaifd
rvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckhk
ypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleap

    Sequence, based on observed residues (ATOM records): (download) 
    >3oapA (A:)
edmpverileaelavepndpvtnicqaadkqlftlvewakriphfselplddqvillrag
wnelliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdk
telgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpa
lrsiglkclehlfffkligdtpidtflmemleap

  • Chain 'B':
    No sequence available.