PDB entry 3o90

View 3o90 on RCSB PDB site
Description: High resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into catalytic mechanism and inhibition by aldehydes
Class: hydrolase
Keywords: Nicotinamidase, HYDROLASE
Deposited on 2010-08-03, released 2011-01-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-01-12, with a file datestamp of 2011-01-07.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: 0.22
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nicotinamidase
    Species: STREPTOCOCCUS PNEUMONIAE [TaxId:170187]
    Gene: SP_1583
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3o90a1, d3o90a2
  • Chain 'B':
    Compound: Nicotinamidase
    Species: STREPTOCOCCUS PNEUMONIAE [TaxId:170187]
    Gene: SP_1583
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3o90b1, d3o90b2
  • Chain 'C':
    Compound: Nicotinamidase
    Species: STREPTOCOCCUS PNEUMONIAE [TaxId:170187]
    Gene: SP_1583
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3o90c1, d3o90c2
  • Chain 'D':
    Compound: Nicotinamidase
    Species: STREPTOCOCCUS PNEUMONIAE [TaxId:170187]
    Gene: SP_1583
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3o90d1, d3o90d2
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3o90A (A:)
mgsshhhhhhssglvprgshmtkalisidytedfvadsgkltagapaqaisdaiskvtrl
afergdyifftidaheendcfhpesklfpphnligtsgrnlygdlgifyqehgsdsrvfw
mdkrhysafsgtdldirlrerrvstviltgvltdicvlhtaidaynlgydieivkpavas
iwpenhqfalghfkntlgaklvdenlnelfe

    Sequence, based on observed residues (ATOM records): (download) 
    >3o90A (A:)
tkalisidytedfvadsgkltagapaqaisdaiskvtrlafergdyifftidahedcfhp
esklfpphnligtsgrnlygdlgifyqehgsdsrvfwmdkrhysafsgtdldirlrerrv
stviltgvltdicvlhtaidaynlgydieivkpavasiwpenhqfalghfkntlgaklvd
enlnelf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3o90B (B:)
mgsshhhhhhssglvprgshmtkalisidytedfvadsgkltagapaqaisdaiskvtrl
afergdyifftidaheendcfhpesklfpphnligtsgrnlygdlgifyqehgsdsrvfw
mdkrhysafsgtdldirlrerrvstviltgvltdicvlhtaidaynlgydieivkpavas
iwpenhqfalghfkntlgaklvdenlnelfe

    Sequence, based on observed residues (ATOM records): (download) 
    >3o90B (B:)
tkalisidytedfvadsgkltagapaqaisdaiskvtrlafergdyifftidaheendcf
hpesklfpphnligtsgrnlygdlgifyqehgsdsrvfwmdkrhysafsgtdldirlrer
rvstviltgvltdicvlhtaidaynlgydieivkpavasiwpenhqfalghfkntlgakl
vdenlnelf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3o90C (C:)
mgsshhhhhhssglvprgshmtkalisidytedfvadsgkltagapaqaisdaiskvtrl
afergdyifftidaheendcfhpesklfpphnligtsgrnlygdlgifyqehgsdsrvfw
mdkrhysafsgtdldirlrerrvstviltgvltdicvlhtaidaynlgydieivkpavas
iwpenhqfalghfkntlgaklvdenlnelfe

    Sequence, based on observed residues (ATOM records): (download) 
    >3o90C (C:)
tkalisidytedfvadsgkltagapaqaisdaiskvtrlafergdyifftidahefpphn
litsgrnlygdlgifyqehgsdsrvfwmdkrhysafsgtdldirlrerrvstviltgvlt
dicvlhtaidaynlgydieivkpavasiwpenhqfalghfkntlgaklvdenlnelf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3o90D (D:)
mgsshhhhhhssglvprgshmtkalisidytedfvadsgkltagapaqaisdaiskvtrl
afergdyifftidaheendcfhpesklfpphnligtsgrnlygdlgifyqehgsdsrvfw
mdkrhysafsgtdldirlrerrvstviltgvltdicvlhtaidaynlgydieivkpavas
iwpenhqfalghfkntlgaklvdenlnelfe

    Sequence, based on observed residues (ATOM records): (download) 
    >3o90D (D:)
tkalisidytedfvadsgkltagapaqaisdaiskvtrlafergdyifftidahedcfhp
esklfpphnligtsgrnlygdlgifyqehgsdsrvfwmdkrhysafsgtdldirlrerrv
stviltgvltdicvlhtaidaynlgydieivkpavasiwpenhqfalghfkntlgaklvd
enlnelf