PDB entry 3o8y

View 3o8y on RCSB PDB site
Description: Stable-5-Lipoxygenase
Class: oxidoreductase
Keywords: PLAT, LOX, Dioxygenase, Coactosin like protein, Five Lipoxygenase Activating Protein, Nuclear membrane, cytosol, OXIDOREDUCTASE
Deposited on 2010-08-03, released 2011-01-19
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-02-09, with a file datestamp of 2011-02-04.
Experiment type: XRAY
Resolution: 2.39 Å
R-factor: 0.183
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Arachidonate 5-lipoxygenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALOX5, LOG5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09917 (Start-690)
      • expression tag (2-8)
      • expression tag (8)
      • expression tag (8)
      • expression tag (8)
      • expression tag (8)
      • expression tag (8)
      • expression tag (8)
      • engineered (33-34)
      • see remark 999 (60-61)
      • engineered (92-93)
      • engineered (257)
      • engineered (578)
      • engineered (670-672)
      • expression tag (2-3)
      • expression tag (7)
  • Chain 'B':
    Compound: Arachidonate 5-lipoxygenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALOX5, LOG5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09917 (Start-690)
      • engineered (33-34)
      • see remark 999 (60-61)
      • engineered (92-93)
      • engineered (257)
      • engineered (578)
      • engineered (670-672)
    Domains in SCOPe 2.06: d3o8yb1, d3o8yb2
  • Heterogens: FE2, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3o8yB (B:)
mgsshhhhhhssglvprgshmpsytvtvatgsqehagtddyiylslvgsagcsekhlldk
gsfergavdsydvtvdeelgeiqlvriekrkygsnddwylkyitlktphgdyiefpcyrw
itgdvevvlrdgraklarddqihilkqhrrkeletrqkqyrwmewnpgfplsidakchkd
lprdiqfdsekgvdfvlnyskamenlfinrfmhmfqsswndfadfekifvkisntiserv
mnhwqedlmfgyqflnganpvlirrctelpeklpvttemvecslerqlsleqevqqgnif
ivdfelldgidanktdpctlqflaapicllyknlankivpiaiqlnqipgdenpiflpsd
akydwllakiwvrssdfhvhqtithllrthlvsevfgiamyrqlpavhpifkllvahvrf
tiaintkareqlicecglfdkanatgggghvqmvqramkdltyaslcfpeaikargmesk
edipyyfyrddgllvweairtftaevvdiyyegdqvveedpelqdfvndvyvygmrgrks
sgfpksvksreqlseyltvviftasaqhaavnfgqydwaswipnapptmrappptakgvv
tieqivdtlpdrgrscwhlgavwalsqfqenelflgmypeehfiekpvkeamarfrknle
aivsviaernenlqlpyyylspdripnsvai

    Sequence, based on observed residues (ATOM records): (download) 
    >3o8yB (B:)
psytvtvatgsqehagtddyiylslvgsagcsekhlldkgsfergavdsydvtvdeelge
iqlvriekrkygsnddwylkyitlktphgdyiefpcyrwitgdvevvlrdgraklarddq
ihilkqhrrkeletrqkqyrwmewnpgfplsidakchkdlprdiqfdsekgvdfvlnysk
amenlfinrfmhmfqsswndfadfekifvkisntiservmnhwqedlmfgyqflnganpv
lirrctelpeklpvttemvecslerqlsleqevqqgnifivdfelldgidanktdpctlq
flaapicllyknlankivpiaiqlnqipgdenpiflpsdakydwllakiwvrssdfhvhq
tithllrthlvsevfgiamyrqlpavhpifkllvahvrftiaintkareqlicecglfdk
anatgggghvqmvqramkdltyaslcfpeaikargmeskedipyyfyrddgllvweairt
ftaevvdiyyegdqvveedpelqdfvndvyvygmrgrkssgfpksvksreqlseyltvvi
ftasaqhaavnfgqydwaswipnapptmrappptakgvvtieqivdtlpdrgrscwhlga
vwalsqfqenelflgmypeehfiekpvkeamarfrknleaivsviaernenlqlpyyyls
pdripnsvai