PDB entry 3o4t

View 3o4t on RCSB PDB site
Description: Crystal Structure of HePTP with an Open WPD Loop and Partially Depleted Active Site
Class: hydrolase
Keywords: heptp, human hematopoietic tyrosine phosphatase catalytic domain mutant, lc-ptp, ptpn7, hydrolase
Deposited on 2010-07-27, released 2010-11-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-02-09, with a file datestamp of 2011-02-04.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.202
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein phosphatase non-receptor type 7
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN7
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35236 (12-End)
      • engineered mutation (40)
    Domains in SCOPe 2.08: d3o4ta_
  • Heterogens: SO4, TAR, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3o4tA (A:)
mgsdkihhhhhhntprevtlhflrtaghpltrwalqrqppdpkqleeeflkipsnfvspe
dldipghaskdryktilpnpqsrvclgraqsqedgdyinanyirgydgkekvyiatqgpm
pntvsdfwemvwqeevslivmltqlregkekcvhywpteeetygpfqiriqdmkecpeyt
vrqltiqyqeerrsvkhilfsawpdhqtpesagpllrlvaeveespetaahpgpivvhcs
agigrtgcfiatrigcqqlkargevdilgivcqlrldrggmiqtaeqyqflhhtlalyag
qlpeepsp

    Sequence, based on observed residues (ATOM records): (download) 
    >3o4tA (A:)
ntprevtlhflrtaghpltrwalqrqppdpkqleeeflkipsnfvspedldipghaskdr
yktilpnpqsrvclgraqsqedgdyinanyirgydgkekvyiatqgpmpntvsdfwemvw
qeevslivmltqcvhywpteeetygpfqiriqdmkecpeytvrqltiqyqeerrsvkhil
fsawpesagpllrlvaeveespetaahpgpivvhcsagigrtgcfiatrigcqqlkarge
vdilgivcqlrldrggmiqtaeqyqflhhtlalyagqlpee