PDB entry 3o2x

View 3o2x on RCSB PDB site
Description: MMP-13 in complex with selective tetrazole core inhibitor
Class: hydrolase
Keywords: Hydrolase
Deposited on 2010-07-22, released 2011-08-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-08-10, with a file datestamp of 2011-08-05.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.178
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: collagenase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP13
    Database cross-references and differences (RAF-indexed):
    • Uniprot P45452
      • expression tag (0)
    Domains in SCOPe 2.08: d3o2xa1, d3o2xa2
  • Chain 'B':
    Compound: collagenase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP13
    Database cross-references and differences (RAF-indexed):
    • Uniprot P45452 (1-163)
      • expression tag (0)
    Domains in SCOPe 2.08: d3o2xb1, d3o2xb2
  • Chain 'C':
    Compound: collagenase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP13
    Database cross-references and differences (RAF-indexed):
    • Uniprot P45452
      • expression tag (0)
    Domains in SCOPe 2.08: d3o2xc1, d3o2xc2
  • Chain 'D':
    Compound: collagenase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP13
    Database cross-references and differences (RAF-indexed):
    • Uniprot P45452 (1-163)
      • expression tag (0)
    Domains in SCOPe 2.08: d3o2xd1, d3o2xd2
  • Heterogens: 3O2, ZN, CA, SO4, EPE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3o2xA (A:)
anvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslyg

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3o2xB (B:)
anvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslyg

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3o2xC (C:)
anvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslyg

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3o2xD (D:)
anvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslyg