PDB entry 3nz0

View 3nz0 on RCSB PDB site
Description: Non-phosphorylated TYK2 kinase with CMP6
Class: transferase
Keywords: protein kinase, tyrosine phosphorylation, TRANSFERASE
Deposited on 2010-07-15, released 2010-10-20
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-02-02, with a file datestamp of 2011-01-28.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.211
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Non-receptor tyrosine-protein kinase TYK2
    Species: Homo sapiens [TaxId:9606]
    Gene: TYK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29597 (Start-294)
      • engineered mutation (141)
      • expression tag (295-296)
    Domains in SCOPe 2.06: d3nz0a1, d3nz0a2
  • Heterogens: IZA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3nz0A (A:)
mgspasdptvfhkrylkkirdlgeghfgkvslycydptndgtgemvavkalkadcgpqhr
sgwkqeidilrtlyhehiikykgccedqgekslqlvmeyvplgslrdylprhsiglaqll
lfaqqicegmaylhaqhyihrnlaarnvlldndrlvkigdfglakavpegheyyrvredg
dspvfwyapeclkeykfyyasdvwsfgvtlyellthcdssqspptkfleligiaqgqmtv
lrltellergerlprpdkcpcevyhlmkncweteasfrptfenlipilktvhekyrhhhh
hh

    Sequence, based on observed residues (ATOM records): (download) 
    >3nz0A (A:)
dptvfhkrylkkirdlgeghfgkvslycydptndgtgemvavkalkadcgpqhrsgwkqe
idilrtlyhehiikykgccedqgekslqlvmeyvplgslrdylprhsiglaqlllfaqqi
cegmaylhaqhyihrnlaarnvlldndrlvkigdfglakavpegheyyrvredgdspvfw
yapeclkeykfyyasdvwsfgvtlyellthcdssqspptkfleligtvlrltellerger
lprpdkcpcevyhlmkncweteasfrptfenlipilktvhekyrh