PDB entry 3nww

View 3nww on RCSB PDB site
Description: P38 Alpha kinase complexed with a 2-aminothiazol-5-yl-pyrimidine based inhibitor
Class: transferase/transferase inhibitor
Keywords: P38 MAP KINASE, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2010-07-12, released 2010-09-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-02, with a file datestamp of 2020-08-28.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 14
    Species: Homo sapiens [TaxId:9606]
    Gene: CSBP, CSBP1, CSBP2, CSPB1, MAPK14, MXI2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3nwwa_
  • Heterogens: 3NW, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3nwwA (A:)
mahhhhhsqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkk
lsrpfqsiihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadln
nivkcqkltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarh
tddemtgyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlkl
ilrlvgtpgaellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsd
kritaaqalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppld
qeemes

    Sequence, based on observed residues (ATOM records): (download) 
    >3nwwA (A:)
rptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsiih
akrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltd
dhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtrwyrapeim
lnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkisses
arnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdp
ddepvadpydqsfesrdllidewksltydevisfvpppl