PDB entry 3num

View 3num on RCSB PDB site
Description: Substrate induced remodeling of the active site regulates HtrA1 activity
Class: hydrolase
Keywords: serine protease, DegP, HtrA, protease, HYDROLASE
Deposited on 2010-07-07, released 2011-02-23
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-03-30, with a file datestamp of 2011-03-25.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: 0.244
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine protease HTRA1
    Species: Homo sapiens [TaxId:9606]
    Gene: HTRA1, HTRA, PRSS11
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q92743
      • engineered mutation (171)
    Domains in SCOPe 2.05: d3numa_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3numA (A:)
mgqedpnslrhkynfiadvvekiapavvhielfrklpfskrevpvasgsgfivsedgliv
tnahvvtnkhrvkvelkngatyeakikdvdekadialikidhqgklpvlllgrsselrpg
efvvaigspfslqntvttgivsttqrggkelglrnsdmdyiqtdaiinygnaggplvnld
gevigintlkvtagisfaipsdkikkflteshdrqakgkaitkkkyigirmmsltsskak
elkdrhrdfpdvisgayiievipdtpaeagglkendviisingqsvvsandvsdvikres
tlnmvvrrgnedimitvipeeidplehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3numA (A:)
dpnslrhkynfiadvvekiapavvhielfrklpfskrevpvasgsgfivsedglivtnah
vvtnkhrvkvelkngatyeakikdvdekadialikidhqgklpvlllgrsselrpgefvv
aigsntvttgivsttdyiqtdaiinygnaggplvnldgevigintlkvtagisfaipsdk
ikkflteshd