PDB entry 3nud

View 3nud on RCSB PDB site
Description: The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis complexed with phenylalanine
Class: transferase
Keywords: Mycobacterium tuberculosis, DAH7P synthase, Shikimate pathway, Aromatic biosynthesis, Evolutionary relationships, Transferase, Phe-bound, Augmented TIM-barrel structure
Deposited on 2010-07-06, released 2010-07-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-02-22, with a file datestamp of 2012-02-17.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.215
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: Rv2178c
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3nuda_
  • Chain 'B':
    Compound: Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: Rv2178c
    Database cross-references and differences (RAF-indexed):
    • Uniprot O53512 (2-463)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d3nudb1, d3nudb2
  • Heterogens: PHE, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3nudA (A:)
gamnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppv
tvpseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygas
mpvvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasa
amnlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnl
qtaeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqv
ianpvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatg
hqviwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvt
eclggaqdisetdlagryetacdprlntqqslelaflvaemlrd

    Sequence, based on observed residues (ATOM records): (download) 
    >3nudA (A:)
wtvdipipslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtvpseiv
rlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmpvvkva
riagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaamnlvra
ltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqtaeiya
shealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqvianpvgv
klgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghqviwqc
dpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvtyetacdp
rlntqqslelaflvaemlrd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3nudB (B:)
gamnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppv
tvpseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygas
mpvvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasa
amnlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnl
qtaeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqv
ianpvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatg
hqviwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvt
eclggaqdisetdlagryetacdprlntqqslelaflvaemlrd

    Sequence, based on observed residues (ATOM records): (download) 
    >3nudB (B:)
gamnwtvdipipplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtvpsei
vrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmpvvkv
ariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaamnlvr
altssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqtaeiy
ashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqvianpvg
vklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghqviwq
cdpmhgnthesfktrhfdrivdevqgffevhralgthpggihveitgenvtagryetacd
prlntqqslelaflvaemlrd