PDB entry 3nsq

View 3nsq on RCSB PDB site
Description: Crystal structure of tetrameric RXRalpha-LBD complexed with antagonist danthron
Class: transcription
Keywords: nuclear receptor retinoic x recepor alpha ligand binding domain antagonist danthron, TRANSCRIPTION
Deposited on 2010-07-02, released 2010-11-17
The last revision prior to the SCOPe 2.01 freeze date was dated 2010-11-17, with a file datestamp of 2010-11-12.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.265
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Retinoid X receptor, alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: RXRA, NR2B1, RP11-473E2.1-002, hCG_18150
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3nsqa_
  • Chain 'B':
    Compound: Retinoid X receptor, alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: RXRA, NR2B1, RP11-473E2.1-002, hCG_18150
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3nsqb_
  • Heterogens: CHZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3nsqA (A:)
tssanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvew
akriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagv
gaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyaslea
yckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleaphqmt

    Sequence, based on observed residues (ATOM records): (download) 
    >3nsqA (A:)
dpvtnicqaadkqlftlvewakriphfselplddqvillragwnelliasfshrsiavkd
gillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdktelgclraivlfnpdskg
lsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalrsiglkclehlfffkli
gdtpidtflmeml

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3nsqB (B:)
tssanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvew
akriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagv
gaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyaslea
yckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleaphqmt

    Sequence, based on observed residues (ATOM records): (download) 
    >3nsqB (B:)
pvtnicqaadkqlftlvewakriphfselplddqvillragwnelliasfshrsiavkdg
illatglhvhrnsahsagvgaifdrvltelvskmrdmqmdktelgclraivlfnpdskgl
snpaevealrekvyasleayckhkypeqpgrfaklllrlpalrsiglkclehlfffklig
dtpidtflmemleaphqmt