PDB entry 3noc

View 3noc on RCSB PDB site
Description: Designed ankyrin repeat protein (DARPin) binders to AcrB: Plasticity of the Interface
Deposited on 2010-06-25, released 2011-05-18
The last revision was dated 2011-05-18, with a file datestamp of 2011-05-13.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.243
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acriflavine resistance protein B
    Species: Escherichia coli [TaxId:83333]
    Gene: acrB, acrE, b0462, JW0451
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Acriflavine resistance protein B
    Species: Escherichia coli [TaxId:83333]
    Gene: acrB, acrE, b0462, JW0451
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Acriflavine resistance protein B
    Species: Escherichia coli [TaxId:83333]
    Gene: acrB, acrE, b0462, JW0451
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Designed ankyrin repeat protein
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 3NOC
  • Chain 'E':
    Compound: Designed ankyrin repeat protein
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 3NOC
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.07, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3nocA (A:)
    mpnffidrpifawviaiiimlagglailklpvaqyptiappavtisasypgadaktvqdt
    vtqvieqnmngidnlmymssnsdstgtvqitltfesgtdadiaqvqvqnklqlampllpq
    evqqqgvsvekssssflmvvgvintdgtmtqedisdyvaanmkdaisrtsgvgdvqlfgs
    qyamriwmnpnelnkfqltpvdvitaikaqnaqvaagqlggtppvkgqqlnasiiaqtrl
    tsteefgkillkvnqdgsrvllrdvakielggenydiiaefngqpasglgiklatganal
    dtaaairaelakmepffpsglkivypydttpfvkisihevvktlveaiilvflvmylflq
    nfratliptiavpvvllgtfavlaafgfsintltmfgmvlaigllvddaivvvenvervm
    aeeglppkeatrksmgqiqgalvgiamvlsavfvpmaffggstgaiyrqfsitivsamal
    svlvaliltpalcatmlkpiakgdhgegkkgffgwfnrmfeksthhytdsvggilrstgr
    ylvlyliivvgmaylfvrlpssflpdedqgvfmtmvqlpagatqertqkvlnevthyylt
    keknnvesvfavngfgfagrgqntgiafvslkdwadrpgeenkveaitmratrafsqikd
    amvfafnlpaivelgtatgfdfelidqaglghekltqarnqllaeaakhpdmltsvrpng
    ledtpqfkididqekaqalgvsindinttlgaawggsyvndfidrgrvkkvyvmseakyr
    mlpddigdwyvraadgqmvpfsafsssrweygsprlerynglpsmeilgqaapgkstgea
    melmeqlasklptgvgydwtgmsyqerlsgnqapslyaislivvflclaalyeswsipfs
    vmlvvplgvigallaatfrgltndvyfqvgllttiglsaknailivefakdlmdkegkgl
    ieatldavrmrlrpilmtslafilgvmplvistgagsgaqnavgtgvmggmvtatvlaif
    fvpvffvvvrrrfsrknediehshtvdhh
    

    Sequence, based on observed residues (ATOM records):
    >3nocA (A:)
    mpnffidrpifawviaiiimlagglailklpvaqyptiappavtisasypgadaktvqdt
    vtqvieqnmngidnlmymssnsdstgtvqitltfesgtdadiaqvqvqnklqlampllpq
    evqqqgvsvekssssflmvvgvintdgtmtqedisdyvaanmkdaisrtsgvgdvqlfgs
    qyamriwmnpnelnkfqltpvdvitaikaqnaqvaagqlggtppvkgqqlnasiiaqtrl
    tsteefgkillkvnqdgsrvllrdvakielggenydiiaefngqpasglgiklatganal
    dtaaairaelakmepffpsglkivypydttpfvkisihevvktlveaiilvflvmylflq
    nfratliptiavpvvllgtfavlaafgfsintltmfgmvlaigllvddaivvvenvervm
    aeeglppkeatrksmgqiqgalvgiamvlsavfvpmaffggstgaiyrqfsitivsamal
    svlvaliltpalcatmlkpiakgdhgegkkgffgwfnrmfeksthhytdsvggilrstgr
    ylvlyliivvgmaylfvrlpssflpdedqgvfmtmvqlpagatqertqkvlnevthyylt
    keknnvesvfavngfgfagrgqntgiafvslkdwadrpgeenkveaitmratrafsqikd
    amvfafnlpaigfdfelidqaglghekltqarnqllaeaakhpdmltsvrpngledtpqf
    kididqekaqalgvsindinttlgaawggsyvndfidrgrvkkvyvmseakyrmlpddig
    dwyvraadgqmvpfsafsssrweygsprlerynglpsmeilgqaapgkstgeamelmeql
    asklptgvgydwtgmsyqqapslyaislivvflclaalyeswsipfsvmlvvplgvigal
    laatfrgltndvyfqvgllttiglsaknailivefakdlmdkegkglieatldavrmrlr
    pilmtslafilgvmplvistgagsgaqnavgtgvmggmvtatvlaiffvpvffvvvrrrf
    srdiehsh
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3nocB (B:)
    mpnffidrpifawviaiiimlagglailklpvaqyptiappavtisasypgadaktvqdt
    vtqvieqnmngidnlmymssnsdstgtvqitltfesgtdadiaqvqvqnklqlampllpq
    evqqqgvsvekssssflmvvgvintdgtmtqedisdyvaanmkdaisrtsgvgdvqlfgs
    qyamriwmnpnelnkfqltpvdvitaikaqnaqvaagqlggtppvkgqqlnasiiaqtrl
    tsteefgkillkvnqdgsrvllrdvakielggenydiiaefngqpasglgiklatganal
    dtaaairaelakmepffpsglkivypydttpfvkisihevvktlveaiilvflvmylflq
    nfratliptiavpvvllgtfavlaafgfsintltmfgmvlaigllvddaivvvenvervm
    aeeglppkeatrksmgqiqgalvgiamvlsavfvpmaffggstgaiyrqfsitivsamal
    svlvaliltpalcatmlkpiakgdhgegkkgffgwfnrmfeksthhytdsvggilrstgr
    ylvlyliivvgmaylfvrlpssflpdedqgvfmtmvqlpagatqertqkvlnevthyylt
    keknnvesvfavngfgfagrgqntgiafvslkdwadrpgeenkveaitmratrafsqikd
    amvfafnlpaivelgtatgfdfelidqaglghekltqarnqllaeaakhpdmltsvrpng
    ledtpqfkididqekaqalgvsindinttlgaawggsyvndfidrgrvkkvyvmseakyr
    mlpddigdwyvraadgqmvpfsafsssrweygsprlerynglpsmeilgqaapgkstgea
    melmeqlasklptgvgydwtgmsyqerlsgnqapslyaislivvflclaalyeswsipfs
    vmlvvplgvigallaatfrgltndvyfqvgllttiglsaknailivefakdlmdkegkgl
    ieatldavrmrlrpilmtslafilgvmplvistgagsgaqnavgtgvmggmvtatvlaif
    fvpvffvvvrrrfsrknediehshtvdhh
    

    Sequence, based on observed residues (ATOM records):
    >3nocB (B:)
    mpnffidrpifawviaiiimlagglailklpvaqyptiappavtisasypgadaktvqdt
    vtqvieqnmngidnlmymssnsdstgtvqitltfesgtdadiaqvqvqnklqlampllpq
    evqqqgvsvekssssflmvvgvintdgtmtqedisdyvaanmkdaisrtsgvgdvqlfgs
    qyamriwmnpnelnkfqltpvdvitaikaqnaqvaagqlggtppvkgqqlnasiiaqtrl
    tsteefgkillkvnqdgsrvllrdvakielggenydiiaefngqpasglgiklatganal
    dtaaairaelakmepffpsglkivypydttpfvkisihevvktlveaiilvflvmylflq
    nfratliptiavpvvllgtfavlaafgfsintltmfgmvlaigllvddaivvvenvervm
    aeeglppkeatrksmgqiqgalvgiamvlsavfvpmaffggstgaiyrqfsitivsamal
    svlvaliltpalcatmlkpiakgdhgegkkgffgwfnrmfeksthhytdsvggilrstgr
    ylvlyliivvgmaylfvrlpssflpdedqgvfmtmvqlpagatqertqkvlnevthyylt
    keknnvesvfavngfgfagrgqntgiafvslkdwadrpgeenkveaitmratrafsqikd
    amvfafnlpaivtatgfdfelidqaglghekltqarnqllaeaakhpdmltsvrpngled
    tpqfkididqekaqalgvsindinttlgaawggsyvndfidrgrvkkvyvmseakyrmlp
    ddigdwyvraadgqmvpfsafsssrweygsprlerynglpsmeilgqaapgkstgeamel
    meqlasklptgvgydwtgmsyqenqapslyaislivvflclaalyeswsipfsvmlvvpl
    gvigallaatfrgltndvyfqvgllttiglsaknailivefakdlmdkegkglieatlda
    vrmrlrpilmtslafilgvmplvistgagsgaqnavgtgvmggmvtatvlaiffvpvffv
    vvrrrf
    

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3nocC (C:)
    mpnffidrpifawviaiiimlagglailklpvaqyptiappavtisasypgadaktvqdt
    vtqvieqnmngidnlmymssnsdstgtvqitltfesgtdadiaqvqvqnklqlampllpq
    evqqqgvsvekssssflmvvgvintdgtmtqedisdyvaanmkdaisrtsgvgdvqlfgs
    qyamriwmnpnelnkfqltpvdvitaikaqnaqvaagqlggtppvkgqqlnasiiaqtrl
    tsteefgkillkvnqdgsrvllrdvakielggenydiiaefngqpasglgiklatganal
    dtaaairaelakmepffpsglkivypydttpfvkisihevvktlveaiilvflvmylflq
    nfratliptiavpvvllgtfavlaafgfsintltmfgmvlaigllvddaivvvenvervm
    aeeglppkeatrksmgqiqgalvgiamvlsavfvpmaffggstgaiyrqfsitivsamal
    svlvaliltpalcatmlkpiakgdhgegkkgffgwfnrmfeksthhytdsvggilrstgr
    ylvlyliivvgmaylfvrlpssflpdedqgvfmtmvqlpagatqertqkvlnevthyylt
    keknnvesvfavngfgfagrgqntgiafvslkdwadrpgeenkveaitmratrafsqikd
    amvfafnlpaivelgtatgfdfelidqaglghekltqarnqllaeaakhpdmltsvrpng
    ledtpqfkididqekaqalgvsindinttlgaawggsyvndfidrgrvkkvyvmseakyr
    mlpddigdwyvraadgqmvpfsafsssrweygsprlerynglpsmeilgqaapgkstgea
    melmeqlasklptgvgydwtgmsyqerlsgnqapslyaislivvflclaalyeswsipfs
    vmlvvplgvigallaatfrgltndvyfqvgllttiglsaknailivefakdlmdkegkgl
    ieatldavrmrlrpilmtslafilgvmplvistgagsgaqnavgtgvmggmvtatvlaif
    fvpvffvvvrrrfsrknediehshtvdhh
    

    Sequence, based on observed residues (ATOM records):
    >3nocC (C:)
    mpnffidrpifawviaiiimlagglailklpvaqyptiappavtisasypgadaktvqdt
    vtqvieqnmngidnlmymssnsdstgtvqitltfesgtdadiaqvqvqnklqlampllpq
    evqqqgvsvekssssflmvvgvintdgtmtqedisdyvaanmkdaisrtsgvgdvqlfgs
    qyamriwmnpnelnkfqltpvdvitaikaqnaqvaagqlggtppvkgqqlnasiiaqtrl
    tsteefgkillkvnqdgsrvllrdvakielggenydiiaefngqpasglgiklatganal
    dtaaairaelakmepffpsglkivypydttpfvkisihevvktlveaiilvflvmylflq
    nfratliptiavpvvllgtfavlaafgfsintltmfgmvlaigllvddaivvvenvervm
    aeeglppkeatrksmgqiqgalvgiamvlsavfvpmaffggstgaiyrqfsitivsamal
    svlvaliltpalcatmlkpiakgdhgegkkgffgwfnrmfeksthhytdsvggilrstgr
    ylvlyliivvgmaylfvrlpssflpdedqgvfmtmvqlpagatqertqkvlnevthyylt
    keknnvesvfavngfgfagrgqntgiafvslkdwadrpgeenkveaitmratrafsqikd
    amvfafnlpaivelgtatgfdfelidqaglghekltqarnqllaeaakhpdmltsvrpng
    ledtpqfkididqekaqalgvsindinttlgaawggsyvndfidrgrvkkvyvmseakyr
    mlpddigdwyvraadgqmvpfsafsssrweygsprlerynglpsmeilgqaapgkstgea
    melmeqlasklptgvgydwtgmsyqerlsgnqapslyaislivvflclaalyeswsipfs
    vmlvvplgvigallaatfrgltndvyfqvgllttiglsaknailivefakdlmdkegkgl
    ieatldavrmrlrpilmtslafilgvmplvistgagsgaqnavgtgvmggmvtatvlaif
    fvpvffvvvrrrfs
    

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3nocD (D:)
    mrgshhhhhhgsdlgkklleaaragqddevrilmangadvnardftgwtplhlaahfghl
    eivevllkngadvnakdslgvtplhlaarrghleivevllkngadvnasdshgftplhla
    akrghleivevllkngadvnaqdkfgktafdisidngnedlaeilqkln
    

    Sequence, based on observed residues (ATOM records):
    >3nocD (D:)
    dlgkklleaaragqddevrilmangadvnardftgwtplhlaahfghleivevllkngad
    vnakdslgvtplhlaarrghleivevllkngadvnasdshgftplhlaakrghleivevl
    lkngadvnaqdkfgktafdisidngnedlaeilq
    

  • Chain 'E':
    Sequence, based on SEQRES records:
    >3nocE (E:)
    mrgshhhhhhgsdlgkklleaaragqddevrilmangadvnardftgwtplhlaahfghl
    eivevllkngadvnakdslgvtplhlaarrghleivevllkngadvnasdshgftplhla
    akrghleivevllkngadvnaqdkfgktafdisidngnedlaeilqkln
    

    Sequence, based on observed residues (ATOM records):
    >3nocE (E:)
    lgkklleaaragqddevrilmangadvnardftgwtplhlaahfghleivevllkngadv
    nakdslgvtplhlaarrghleivevllkngadvnasdshgftplhlaakrghleivevll
    kngadvnaqdkfgktafdisidngnedlaeil