PDB entry 3njy

View 3njy on RCSB PDB site
Description: Crystal structure of JMJD2A complexed with 5-carboxy-8-hydroxyquinoline
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: OXIDOREDUCTASE, CHROMATIN REGULATOR, TRANSCRIPTION REGULATION, DOUBLE-STRANDED BETA HELIX, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on 2010-06-18, released 2010-12-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-12-15, with a file datestamp of 2010-12-10.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.182
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: lysine-specific demethylase 4a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3njya_
  • Chain 'B':
    Compound: lysine-specific demethylase 4a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3njyb_
  • Heterogens: NI, ZN, 8XQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3njyA (A:)
mhhhhhhssgvdlgtenlyfqsmasesetlnpsarimtfyptmeefrnfsryiayiesqg
ahraglakvvppkewkprasyddiddlvipapiqqlvtgqsglftqyniqkkamtvrefr
kiansdkyctprysefeelerkywknltfnppiygadvngtlyekhvdewnigrlrtild
lvekesgitiegvntpylyfgmwktsfawhtedmdlysinylhfgepkswysvppehgkr
lerlakgffpgsaqsceaflrhkmtlisplmlkkygipfdkvtqeagefmitfpygyhag
fnhgfncaestnfatrrwieygkqavlcscrkdmvkismdvfvrkfqperyklwkagkdn
tvidhtlptpeaaeflkesel

    Sequence, based on observed residues (ATOM records): (download) 
    >3njyA (A:)
lnpsarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyddiddlvi
papiqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerkywknltf
nppiygadvngtlyekhvdewnigrlrtildlvekesgitiegvntpylyfgmwktsfaw
htedmdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrhkmtlisp
lmlkkygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieygkqavlcs
crkdmvkismdvfvrkfqperyklwkagkdntvidhtlptpeaaefl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3njyB (B:)
mhhhhhhssgvdlgtenlyfqsmasesetlnpsarimtfyptmeefrnfsryiayiesqg
ahraglakvvppkewkprasyddiddlvipapiqqlvtgqsglftqyniqkkamtvrefr
kiansdkyctprysefeelerkywknltfnppiygadvngtlyekhvdewnigrlrtild
lvekesgitiegvntpylyfgmwktsfawhtedmdlysinylhfgepkswysvppehgkr
lerlakgffpgsaqsceaflrhkmtlisplmlkkygipfdkvtqeagefmitfpygyhag
fnhgfncaestnfatrrwieygkqavlcscrkdmvkismdvfvrkfqperyklwkagkdn
tvidhtlptpeaaeflkesel

    Sequence, based on observed residues (ATOM records): (download) 
    >3njyB (B:)
lnpsarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyddiddlvi
papiqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerkywknltf
nppiygadvngtlyekhvdewnigrlrtildlvekesgitiegvntpylyfgmwktsfaw
htedmdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrhkmtlisp
lmlkkygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieygkqavlcs
crkdmvkismdvfvrkfqperyklwkagkdntvidhtlptpeaaefl