PDB entry 3nfl

View 3nfl on RCSB PDB site
Description: Crystal structure of the PTPN4 PDZ domain complexed with the C-terminus of the GluN2A NMDA receptor subunit
Class: protein binding
Keywords: PDZ-PDZ-binding site complex, PROTEIN BINDING
Deposited on 2010-06-10, released 2011-08-24
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-11-30, with a file datestamp of 2011-11-25.
Experiment type: XRAY
Resolution: 1.91 Å
R-factor: 0.218
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tyrosine-protein phosphatase non-receptor type 4
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3nfla_
  • Chain 'B':
    Compound: tyrosine-protein phosphatase non-receptor type 4
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3nflb_
  • Chain 'C':
    Compound: tyrosine-protein phosphatase non-receptor type 4
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3nflc_
  • Chain 'D':
    Compound: tyrosine-protein phosphatase non-receptor type 4
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3nfld_
  • Chain 'E':
    Compound: Glutamate [NMDA] receptor subunit epsilon-1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Glutamate [NMDA] receptor subunit epsilon-1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Glutamate [NMDA] receptor subunit epsilon-1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Glutamate [NMDA] receptor subunit epsilon-1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3nflA (A:)
    gsspekptpnggiphdnlvlirmkpdengrfgfnvkggydqkmpvivsrvapgtpadlcv
    prlnegdqvvlingrdiaehthdqvvlfikascerhsgelmllvrpn
    

    Sequence, based on observed residues (ATOM records): (download)
    >3nflA (A:)
    hdnlvlirmkpdengrfgfnvkggydqkmpvivsrvapgtpadlcvprlnegdqvvling
    rdiaehthdqvvlfikascerhsgelmllvrp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3nflB (B:)
    gsspekptpnggiphdnlvlirmkpdengrfgfnvkggydqkmpvivsrvapgtpadlcv
    prlnegdqvvlingrdiaehthdqvvlfikascerhsgelmllvrpn
    

    Sequence, based on observed residues (ATOM records): (download)
    >3nflB (B:)
    hdnlvlirmkpdengrfgfnvkggydqkmpvivsrvapgtpadlcvprlnegdqvvling
    rdiaehthdqvvlfikascsgelmllvrp
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >3nflC (C:)
    gsspekptpnggiphdnlvlirmkpdengrfgfnvkggydqkmpvivsrvapgtpadlcv
    prlnegdqvvlingrdiaehthdqvvlfikascerhsgelmllvrpn
    

    Sequence, based on observed residues (ATOM records): (download)
    >3nflC (C:)
    phdnlvlirmkpdengrfgfnvkggydqkmpvivsrvapgtpadlcvprlnegdqvvlin
    grdiaehthdqvvlfikascelmllvrpn
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >3nflD (D:)
    gsspekptpnggiphdnlvlirmkpdengrfgfnvkggydqkmpvivsrvapgtpadlcv
    prlnegdqvvlingrdiaehthdqvvlfikascerhsgelmllvrpn
    

    Sequence, based on observed residues (ATOM records): (download)
    >3nflD (D:)
    dnlvlirmkpdengrfgfnvkggydqkmpvivsrvapgtpadlcvprlnegdqvvlingr
    diaehthdqvvlfikascegelmllvrpn
    

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.