PDB entry 3nal

View 3nal on RCSB PDB site
Description: SR Ca(2+)-ATPase in the HnE2 state complexed with the Thapsigargin derivative DTB
Class: hydrolase
Keywords: SERCA, P-Type ATPase, Ca2+-ATPase, Thapsigargin, Prostate Cancer, Calcium Transport, Endoplasmic Reticulum, Hydrolase, Ion Transport, Sarcoplasmic Reticulum, Transmembrane, Transport
Deposited on 2010-06-02, released 2010-06-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-09-22, with a file datestamp of 2010-09-17.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: 0.255
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: SERCA1a
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3nala1, d3nala2, d3nala3, d3nala4
  • Heterogens: K, MG, DBK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3nalA (A:)
    meaahsksteeclayfgvsettgltpdqvkrhlekyghnelpaeegkslwelvieqfedl
    lvrilllaacisfvlawfeegeetitafvepfvillilianaivgvwqernaenaiealk
    eyepemgkvyradrksvqrikardivpgdivevavgdkvpadirilsiksttlrvdqsil
    tgesvsvikhtepvpdpravnqdkknmlfsgtniaagkalgivattgvsteigkirdqma
    ateqdktplqqkldefgeqlskvislicvavwlinighfndpvhggswirgaiyyfkiav
    alavaaipeglpavittclalgtrrmakknaivrslpsvetlgctsvicsdktgtlttnq
    msvckmfiidkvdgdfcslnefsitgstyapegevlkndkpirsgqfdglvelaticalc
    ndssldfnetkgvyekvgeatetalttlvekmnvfntevrnlskveranacnsvirqlmk
    keftlefsrdrksmsvycspakssraavgnkmfvkgapegvidrcnyvrvgttrvpmtgp
    vkekilsvikewgtgrdtlrclalatrdtppkreemvlddssrfmeyetdltfvgvvgml
    dpprkevmgsiqlcrdagirvimitgdnkgtaiaicrrigifgeneevadraytgrefdd
    lplaeqreacrraccfarvepshkskiveylqsydeitamtgdgvndapalkkaeigiam
    gsgtavaktasemvladdnfstivaaveegraiynnmkqfirylissnvgevvcifltaa
    lglpealipvqllwvnlvtdglpatalgfnppdldimdrpprspkeplisgwlffrymai
    ggyvgaatvgaaawwfmyaedgpgvtyhqlthfmqctedhphfegldceifeapepmtma
    lsvlvtiemcnalnslsenqslmrmppwvniwllgsiclsmslhflilyvdplpmifklk
    aldltqwlmvlkislpvigldeilkfiarnyleg