PDB entry 3na0

View 3na0 on RCSB PDB site
Description: Crystal structure of human CYP11A1 in complex with 20,22-dihydroxycholesterol
Class: Oxidoreductase, Electron transport
Keywords: cytochrome P450, 20, 22-dihydroxycholesterol, side chain cleavage, Structural Genomics, Structural Genomics Consortium, SGC, Oxidoreductase, Electron transport
Deposited on 2010-05-31, released 2010-09-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cholesterol side-chain cleavage enzyme, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP11A, CYP11A1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3na0a_
  • Chain 'B':
    Compound: Cholesterol side-chain cleavage enzyme, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP11A, CYP11A1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3na0b_
  • Chain 'C':
    Compound: Adrenodoxin, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: adrenodoxin, ADX, FDX1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3na0c_
  • Chain 'D':
    Compound: Adrenodoxin, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: adrenodoxin, ADX, FDX1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3na0d_
  • Heterogens: HEM, 2DC, FES, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3na0A (A:)
sprpfneipspgdngwlnlyhfwretgthkvhlhhvqnfqkygpiyreklgnvesvyvid
pedvallfksegpnperflippwvayhqyyqrpigvllkksaawkkdrvalnqevmapea
tknflplldavsrdfvsvlhrrikkagsgnysgdisddlfrfafesitnvifgerqgmle
evvnpeaqrfidaiyqmfhtsvpmlnlppdlfrlfrtktwkdhvaawdvifskadiytqn
fywelrqkgsvhhdyrgilyrllgdskmsfedikanvtemlaggvdttsmtlqwhlyema
rnlkvqdmlraevlaarhqaqgdmatmlqlvpllkasiketlrlhpisvtlqrylvndlv
lrdymipaktlvqvaiyalgreptfffdpenfdptrwlskdknityfrnlgfgwgvrqcl
grriaelemtiflinmlenfrveiqhlsdvgttfnlilmpekpisftfwpf

    Sequence, based on observed residues (ATOM records): (download) 
    >3na0A (A:)
prpfneipspgdngwlnlyhfwretgthkvhlhhvqnfqkygpiyreklgnvesvyvidp
edvallfksegpnperflippwvayhqyyqrpigvllkksaawkkdrvalnqevmapeat
knflplldavsrdfvsvlhrrikkagsgnysgdisddlfrfafesitnvifgerqgmlee
vvnpeaqrfidaiyqmfhtsvpmlnlppdlfrlfrtktwkdhvaawdvifskadiytqnf
ywelrqkgsvhhdyrgilyrllgdskmsfedikanvtemlaggvdttsmtlqwhlyemar
nlkvqdmlraevlaarhqaqgdmatmlqlvpllkasiketlrlhpisvtlqrylvndlvl
rdymipaktlvqvaiyalgreptfffdpenfdptrwlskdknityfrnlgfgwgvrqclg
rriaelemtiflinmlenfrveiqhlsdvgttfnlilmpekpisftfwpf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3na0B (B:)
sprpfneipspgdngwlnlyhfwretgthkvhlhhvqnfqkygpiyreklgnvesvyvid
pedvallfksegpnperflippwvayhqyyqrpigvllkksaawkkdrvalnqevmapea
tknflplldavsrdfvsvlhrrikkagsgnysgdisddlfrfafesitnvifgerqgmle
evvnpeaqrfidaiyqmfhtsvpmlnlppdlfrlfrtktwkdhvaawdvifskadiytqn
fywelrqkgsvhhdyrgilyrllgdskmsfedikanvtemlaggvdttsmtlqwhlyema
rnlkvqdmlraevlaarhqaqgdmatmlqlvpllkasiketlrlhpisvtlqrylvndlv
lrdymipaktlvqvaiyalgreptfffdpenfdptrwlskdknityfrnlgfgwgvrqcl
grriaelemtiflinmlenfrveiqhlsdvgttfnlilmpekpisftfwpf

    Sequence, based on observed residues (ATOM records): (download) 
    >3na0B (B:)
prpfneipspgdngwlnlyhfwretgthkvhlhhvqnfqkygpiyreklgnvesvyvidp
edvallfksegpnperflippwvayhqyyqrpigvllkksaawkkdrvalnqevmapeat
knflplldavsrdfvsvlhrrikkagsgnysgdisddlfrfafesitnvifgerqgmlee
vvnpeaqrfidaiyqmfhtsvpmlnlppdlfrlfrtktwkdhvaawdvifskadiytqnf
ywelrqkgsvhhdyrgilyrllgdskmsfedikanvtemlaggvdttsmtlqwhlyemar
nlkvqdmlraevlaarhqaqgdmatmlqlvpllkasiketlrlhpisvtlqrylvndlvl
rdymipaktlvqvaiyalgreptfffdpenfdptrwlskdknityfrnlgfgwgvrqclg
rriaelemtiflinmlenfrveiqhlsdvgttfnlilmpekpisftfwpf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3na0C (C:)
slldvvvennldidgfgacegtlacstchlifedhiyekldaitdeendmldlaygltdr
srlgcqic

    Sequence, based on observed residues (ATOM records): (download) 
    >3na0C (C:)
fgacegtlacstctdeendmldlalgcq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3na0D (D:)
slldvvvennldidgfgacegtlacstchlifedhiyekldaitdeendmldlaygltdr
srlgcqic

    Sequence, based on observed residues (ATOM records): (download) 
    >3na0D (D:)
fgacegtlacstctdeendmldlalgcq