PDB entry 3n9j

View 3n9j on RCSB PDB site
Description: Structure of human Glutathione Transferase Pi class in complex with Ethacraplatin
Class: transferase
Keywords: transferase, glutathione, detoxification, ethacrynic acid, cisplatin, prodrug, ethacraplatin, platinum
Deposited on 2010-05-30, released 2011-05-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-05-11, with a file datestamp of 2011-05-06.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.18
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutathione S-transferase P
    Species: Homo sapiens [TaxId:9606]
    Gene: FAEES3, GST3, GSTP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3n9ja1, d3n9ja2
  • Chain 'B':
    Compound: Glutathione S-transferase P
    Species: Homo sapiens [TaxId:9606]
    Gene: FAEES3, GST3, GSTP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3n9jb1, d3n9jb2
  • Heterogens: PT, MES, EAA, CA, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3n9jA (A:)
mppytvvyfpvrgrcaalrmlladqgqswkeevvtvetwqegslkasclygqlpkfqdgd
ltlyqsntilrhlgrtlglygkdqqeaalvdmvndgvedlrckyisliytnyeagkddyv
kalpgqlkpfetllsqnqggktfivgdqisfadynlldlllihevlapgcldafpllsay
vgrlsarpklkaflaspeyvnlpingngkq

    Sequence, based on observed residues (ATOM records): (download) 
    >3n9jA (A:)
pytvvyfpvrgrcaalrmlladqgqswkeevvtvetwqegslkasclygqlpkfqdgdlt
lyqsntilrhlgrtlglygkdqqeaalvdmvndgvedlrckyisliytnyeagkddyvka
lpgqlkpfetllsqnqggktfivgdqisfadynlldlllihevlapgcldafpllsayvg
rlsarpklkaflaspeyvnlpingngkq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3n9jB (B:)
mppytvvyfpvrgrcaalrmlladqgqswkeevvtvetwqegslkasclygqlpkfqdgd
ltlyqsntilrhlgrtlglygkdqqeaalvdmvndgvedlrckyisliytnyeagkddyv
kalpgqlkpfetllsqnqggktfivgdqisfadynlldlllihevlapgcldafpllsay
vgrlsarpklkaflaspeyvnlpingngkq

    Sequence, based on observed residues (ATOM records): (download) 
    >3n9jB (B:)
pytvvyfpvrgrcaalrmlladqgqswkeevvtvetwqegslkasclygqlpkfqdgdlt
lyqsntilrhlgrtlglygkdqqeaalvdmvndgvedlrckyisliytnyeagkddyvka
lpgqlkpfetllsqnqggktfivgdqisfadynlldlllihevlapgcldafpllsayvg
rlsarpklkaflaspeyvnlpingngkq