PDB entry 3n96

View 3n96 on RCSB PDB site
Description: Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 1
Deposited on 2010-05-28, released 2010-10-20
The last revision was dated 2010-10-20, with a file datestamp of 2010-10-15.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: 0.237
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Maltose binding protein-CRFR2 alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CRFR2 alpha
    Database cross-references and differences (RAF-indexed):
    • PDB 3N96
  • Chain 'B':
    Compound: Maltose binding protein-CRFR2 alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CRFR2 alpha
    Database cross-references and differences (RAF-indexed):
    • PDB 3N96
  • Chain 'C':
    Compound: Maltose binding protein-CRFR2 alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CRFR2 alpha
    Database cross-references and differences (RAF-indexed):
    • PDB 3N96
  • Chain 'D':
    Compound: Maltose binding protein-CRFR2 alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CRFR2 alpha
    Database cross-references and differences (RAF-indexed):
    • PDB 3N96
  • Chain 'E':
    Compound: Urocortin
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Urocortin
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Urocortin
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Urocortin
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MAL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.07, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3n96A (A:)
    makieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpd
    iifwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliyn
    kdllpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydi
    kdvgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidts
    kvnygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkp
    lgavalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvd
    ealkdaqtnaaaefaallhslleancslalaeellldgwgppldpegpysycnttldqig
    tcwprsaagalverpcpeyfngvkynttrnayreclengtwaskinysqcepilddhhhh
    hh
    

    Sequence, based on observed residues (ATOM records):
    >3n96A (A:)
    kieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdii
    fwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynkd
    llpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydikd
    vgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtskv
    nygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkplg
    avalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvdea
    lkdaqtnaaaefaallhslleancslalaeellldgwgppldpegpysycnttldqigtc
    wprsaagalverpcpeyfngvkynttrnayreclengtwaskinysqcepild
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3n96B (B:)
    makieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpd
    iifwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliyn
    kdllpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydi
    kdvgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidts
    kvnygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkp
    lgavalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvd
    ealkdaqtnaaaefaallhslleancslalaeellldgwgppldpegpysycnttldqig
    tcwprsaagalverpcpeyfngvkynttrnayreclengtwaskinysqcepilddhhhh
    hh
    

    Sequence, based on observed residues (ATOM records):
    >3n96B (B:)
    kieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdii
    fwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynkd
    llpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydikd
    vgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtskv
    nygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkplg
    avalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvdea
    lkdaqtnaaaefaallhslleancslalaeellldgwgppldpegpysycnttldqigtc
    wprsaagalverpcpeyfngvkynttrnayreclengtwaskinysqcepi
    

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3n96C (C:)
    makieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpd
    iifwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliyn
    kdllpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydi
    kdvgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidts
    kvnygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkp
    lgavalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvd
    ealkdaqtnaaaefaallhslleancslalaeellldgwgppldpegpysycnttldqig
    tcwprsaagalverpcpeyfngvkynttrnayreclengtwaskinysqcepilddhhhh
    hh
    

    Sequence, based on observed residues (ATOM records):
    >3n96C (C:)
    kieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdii
    fwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynkd
    llpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydikd
    vgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtskv
    nygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkplg
    avalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvdea
    lkdaqtnaaaefaallhslleancslalaeellldgwgpppysycnttldqigtcwprsa
    agalverpcpeyfngvkynttrnayreclengtwaskinysqcepil
    

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3n96D (D:)
    makieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpd
    iifwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliyn
    kdllpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydi
    kdvgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidts
    kvnygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkp
    lgavalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvd
    ealkdaqtnaaaefaallhslleancslalaeellldgwgppldpegpysycnttldqig
    tcwprsaagalverpcpeyfngvkynttrnayreclengtwaskinysqcepilddhhhh
    hh
    

    Sequence, based on observed residues (ATOM records):
    >3n96D (D:)
    kieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdii
    fwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynkd
    llpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydikd
    vgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtskv
    nygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkplg
    avalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvdea
    lkdaqtnaaaefaallhslleancslalaeellldgwgpppysycnttldqigtcwprsa
    agalverpcpeyfngvkynttrnayreclengtwaskinysqcepild
    

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records:
    >3n96E (E:)
    sqreraeqnriifdsv
    

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records:
    >3n96F (F:)
    sqreraeqnriifdsv
    

  • Chain 'G':
    Sequence, based on SEQRES records:
    >3n96G (G:)
    sqreraeqnriifdsv
    

    Sequence, based on observed residues (ATOM records):
    >3n96G (G:)
    reraeqnriifdsv
    

  • Chain 'H':
    Sequence, based on SEQRES records:
    >3n96H (H:)
    sqreraeqnriifdsv
    

    Sequence, based on observed residues (ATOM records):
    >3n96H (H:)
    eqnriifdsv