SCOPe 2.07: Structural Classification of Proteins

PDB entry 3n82

View 3n82 on RCSB PDB site
Description: T244A mutant of Human mitochondrial aldehyde dehydrogenase, NADH complex
Class: oxidoreductase
Keywords: oxidoreductase, ALDH, Rossmann fold
Deposited on 2010-05-27, released 2011-04-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: aldehyde dehydrogenase, mitochondrial
Species: Homo sapiens [TaxId:9606]
Gene: ALDH2, ALDM
Database cross-references and differences (RAF-indexed):
- Uniprot P05091 (Start-499)
  - engineered mutation (243)
Domains in SCOPe 2.07: d3n82a_
Chain 'B':
Compound: aldehyde dehydrogenase, mitochondrial
Species: Homo sapiens [TaxId:9606]
Gene: ALDH2, ALDM
Database cross-references and differences (RAF-indexed):
- Uniprot P05091 (Start-499)
  - engineered mutation (243)
Domains in SCOPe 2.07: d3n82b_
Chain 'C':
Compound: aldehyde dehydrogenase, mitochondrial
Species: Homo sapiens [TaxId:9606]
Gene: ALDH2, ALDM
Database cross-references and differences (RAF-indexed):
- Uniprot P05091 (Start-499)
  - engineered mutation (243)
Domains in SCOPe 2.07: d3n82c_
Chain 'D':
Compound: aldehyde dehydrogenase, mitochondrial
Species: Homo sapiens [TaxId:9606]
Gene: ALDH2, ALDM
Database cross-references and differences (RAF-indexed):
- Uniprot P05091 (Start-499)
  - engineered mutation (243)
Domains in SCOPe 2.07: d3n82d_
Chain 'E':
Compound: aldehyde dehydrogenase, mitochondrial
Species: Homo sapiens [TaxId:9606]
Gene: ALDH2, ALDM
Database cross-references and differences (RAF-indexed):
- Uniprot P05091 (Start-499)
  - engineered mutation (243)
Domains in SCOPe 2.07: d3n82e_
Chain 'F':
Compound: aldehyde dehydrogenase, mitochondrial
Species: Homo sapiens [TaxId:9606]
Gene: ALDH2, ALDM
Database cross-references and differences (RAF-indexed):
- Uniprot P05091 (Start-499)
  - engineered mutation (243)
Domains in SCOPe 2.07: d3n82f_
Chain 'G':
Compound: aldehyde dehydrogenase, mitochondrial
Species: Homo sapiens [TaxId:9606]
Gene: ALDH2, ALDM
Database cross-references and differences (RAF-indexed):
- Uniprot P05091 (Start-499)
  - engineered mutation (243)
Domains in SCOPe 2.07: d3n82g_
Chain 'H':
Compound: aldehyde dehydrogenase, mitochondrial
Species: Homo sapiens [TaxId:9606]
Gene: ALDH2, ALDM
Database cross-references and differences (RAF-indexed):
- Uniprot P05091 (Start-499)
  - engineered mutation (243)
Domains in SCOPe 2.07: d3n82h_
Heterogens: MG, NA, GAI, EDO, NAD, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>3n82A (A:)
saaatqavpapnqqpevfcnqifinnewhdavsrktfptvnpstgevicqvaegdkedvd
kavkaaraafqlgspwrrmdashrgrllnrladlierdrtylaaletldngkpyvisylv
dldmvlkclryyagwadkyhgktipidgdffsytrhepvgvcgqiipwnfpllmqawklg
palatgnvvvmkvaeqtpltalyvanlikeagfppgvvnivpgfgptagaaiashedvdk
vafagsteigrviqvaagssnlkrvtlelggkspniimsdadmdwaveqahfalffnqgq
cccagsrtfvqediydefversvaraksrvvgnpfdskteqgpqvdetqfkkilgyintg
kqegakllcgggiaadrgyfiqptvfgdvqdgmtiakeeifgpvmqilkfktieevvgra
nnstyglaaavftkdldkanylsqalqagtvwvncydvfgaqspfggykmsgsgrelgey
glqaytevktvtvkvpqkns