PDB entry 3n5g

View 3n5g on RCSB PDB site
Description: Crystal Structure of histidine-tagged human thymidylate synthase
Class: transferase
Keywords: peptide inhibitor, protein-peptide complex, interface inhibitor, TRANSFERASE
Deposited on 2010-05-25, released 2011-06-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-07-24, with a file datestamp of 2013-07-19.
Experiment type: XRAY
Resolution: 2.27 Å
R-factor: 0.168
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: TYMS, TS, OK/SW-cl.29
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3n5ga_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3n5gA (A:)
mrgshhhhhhgsmpvagselprrplppaaqerdaeprpphgelqylgqiqhilrcgvrkd
drtgtgtlsvfgmqaryslrdefpllttkrvfwkgvleellwfikgstnakelsskgvki
wdangsrdfldslgfstreegdlgpvygfqwrhfgaeyrdmesdysgqgvdqlqrvidti
ktnpddrriimcawnprdlplmalppchalcqfyvvnselscqlyqrsgdmglgvpfnia
syalltymiahitglkpgdfihtlgdahiylnhieplkiqlqreprpfpklrilrkveki
ddfkaedfqiegynphptikmemav

    Sequence, based on observed residues (ATOM records): (download) 
    >3n5gA (A:)
pphgelqylgqiqhilrcgvrkddrtgtgtlsvfgmqaryslrdefpllttkrvfwkgvl
eellwfikgstnakelsskgvkdlgpvygfqwrhfgaeyrdmesdysgqgvdqlqrvidt
iktnpddrriimcawnprdlplmalppchalcqfyvvnselscqlyqrsgdmglgvpfni
asyalltymiahitglkpgdfihtlgdahiylnhieplkiqlqreprpfpklrilrkvek
iddfkaedfqiegynphptikme