PDB entry 3n3z
View 3n3z on RCSB PDB site
Description: Crystal structure of PDE9A (E406A) mutant in complex with IBMX
Class: hydrolase/hydrolase inhibitor
Keywords: HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on
2010-05-21, released
2011-04-13
The last revision prior to the SCOPe 2.08 freeze date was dated
2011-04-13, with a file datestamp of
2011-04-08.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: 0.202
AEROSPACI score: 0.29
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
Species: Homo sapiens [TaxId:9606]
Gene: PDE
Database cross-references and differences (RAF-indexed):
- Uniprot O76083 (0-325)
- engineered mutation (225)
Domains in SCOPe 2.08: d3n3za_ - Chain 'B':
Compound: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
Species: Homo sapiens [TaxId:9606]
Gene: PDE
Database cross-references and differences (RAF-indexed):
- Uniprot O76083 (0-325)
- engineered mutation (225)
Domains in SCOPe 2.08: d3n3zb_ - Heterogens: IBM, ZN, MG, CL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>3n3zA (A:)
ptypkyllspetiealrkptfdvwlwepnemlsclehmyhdlglvrdfsinpvtlrrwlf
cvhdnyrnnpfhnfrhcfcvaqmmysmvwlcslqekfsqtdililmtaaichdldhpgyn
ntyqinartelavryndisplenhhcavafqilaepecnifsnippdgfkqirqgmitli
latdmarhaeimdsfkekmenfdysneehmtllkmilikccdisnavrpmevaepwvdcl
leeyfmqsdrekseglpvapfmdrdkvtkataqigfikfvlipmfetvtklfpmveeiml
qplwesrdryeelkriddamkelqkk
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3n3zB (B:)
ptypkyllspetiealrkptfdvwlwepnemlsclehmyhdlglvrdfsinpvtlrrwlf
cvhdnyrnnpfhnfrhcfcvaqmmysmvwlcslqekfsqtdililmtaaichdldhpgyn
ntyqinartelavryndisplenhhcavafqilaepecnifsnippdgfkqirqgmitli
latdmarhaeimdsfkekmenfdysneehmtllkmilikccdisnavrpmevaepwvdcl
leeyfmqsdrekseglpvapfmdrdkvtkataqigfikfvlipmfetvtklfpmveeiml
qplwesrdryeelkriddamkelqkk