PDB entry 3n1f

View 3n1f on RCSB PDB site
Description: Crystal Structure of IhhN bound to CDOFn3
Class: protein binding
Keywords: Binding Sites, Cell Adhesion Molecules, Cell Cycle Proteins, Cell Line, Conserved Sequence, Fibronectins, Hedgehog Proteins, Immunoglobulin G, Membrane Glycoproteins, Membrane Proteins, Protein Binding, Tertiary, Receptors, Cell Surface, Sequence Homology, Signal Transduction, Tumor Suppressor Proteins
Deposited on 2010-05-15, released 2010-06-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-06-19, with a file datestamp of 2013-06-14.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.155
AEROSPACI score: 0.64 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Indian hedgehog protein
    Species: Homo sapiens [TaxId:9606]
    Gene: IHH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3n1fa_
  • Chain 'B':
    Compound: Indian hedgehog protein
    Species: Homo sapiens [TaxId:9606]
    Gene: IHH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3n1fb_
  • Chain 'C':
    Compound: Cell adhesion molecule-related/down-regulated by oncogenes
    Species: Homo sapiens [TaxId:9606]
    Gene: CDON, CDO
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3n1fc_
  • Chain 'D':
    Compound: Cell adhesion molecule-related/down-regulated by oncogenes
    Species: Homo sapiens [TaxId:9606]
    Gene: CDON, CDO
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4KMG0 (3-101)
      • expression tag (0-2)
    Domains in SCOPe 2.07: d3n1fd1, d3n1fd2
  • Heterogens: ZN, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3n1fA (A:)
    gsgpgpgrvvgsrrrpprklvplaykqfspnvpektlgasgryegkiarsserfkeltpn
    ynpdiifkdeentgadrlmtqrckdrlnslaisvmnqwpgvklrvtegwdedghhseesl
    hyegravdittsdrdrnkygllarlaveagfdwvyyeskahvhcsvkse
    

    Sequence, based on observed residues (ATOM records): (download)
    >3n1fA (A:)
    klvplaykqfspnvpektlgasgryegkiarsserfkeltpnynpdiifkdeentgadrl
    mtqrckdrlnslaisvmnqwpgvklrvtegwdedghhseeslhyegravdittsdrdrnk
    ygllarlaveagfdwvyyeskahvhcsvkse
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3n1fB (B:)
    gsgpgpgrvvgsrrrpprklvplaykqfspnvpektlgasgryegkiarsserfkeltpn
    ynpdiifkdeentgadrlmtqrckdrlnslaisvmnqwpgvklrvtegwdedghhseesl
    hyegravdittsdrdrnkygllarlaveagfdwvyyeskahvhcsvkse
    

    Sequence, based on observed residues (ATOM records): (download)
    >3n1fB (B:)
    lvplaykqfspnvpektlgasgryegkiarsserfkeltpnynpdiifkdeentgadrlm
    tqrckdrlnslaisvmnqwpgvklrvtegwdedghhseeslhyegravdittsdrdrnky
    gllarlaveagfdwvyyeskahvhcsvkse
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >3n1fC (C:)
    gstpitgphiayteavsdtqimlkwtyipssnnntpiqgfyiyyrptdsdndsdykrdvv
    egskqwhmighlqpetsydikmqcfneggesefsnvmicetk
    

    Sequence, based on observed residues (ATOM records): (download)
    >3n1fC (C:)
    pitgphiayteavsdtqimlkwtyiptpiqgfyiyyrptdsdndsdykrdvvegskqwhm
    ighlqpetsydikmqcfneggesefsnvmicetk
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3n1fD (D:)
    gstpitgphiayteavsdtqimlkwtyipssnnntpiqgfyiyyrptdsdndsdykrdvv
    egskqwhmighlqpetsydikmqcfneggesefsnvmicetk