PDB entry 3n0t

View 3n0t on RCSB PDB site
Description: human dipeptidil peptidase dpp7 complexed with inhibitor gsk237826a
Deposited on 2010-05-14, released 2010-07-21
The last revision was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dipeptidyl peptidase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: DPP2, DPP7, QPP
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Dipeptidyl peptidase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: DPP2, DPP7, QPP
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Dipeptidyl peptidase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: DPP2, DPP7, QPP
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Dipeptidyl peptidase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: DPP2, DPP7, QPP
    Database cross-references and differences (RAF-indexed):
  • Heterogens: OPY, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.07, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3n0tA (A:)
    gamddpgfqerffqqrldhfnferfgnktfpqrflvsdrfwvrgegpiffytgnegdvwa
    fannsafvaelaaergallvfaehryygkslpfgaqstqrghtelltveqaladfaellr
    alrrdlgaqdapaiafggsyggmlsaylrmkyphlvagalaasapvlavaglgdsnqffr
    dvtadfegqspkctqgvreafrqikdlflqgaydtvrwefgtcqplsdekdltqlfmfar
    naftvlammdypyptdflgplpanpvkvgcdrllseaqritglralaglvynasgsehcy
    diyrlyhscadptgcgtgpdarawdyqacteinltfasnnvtdmfpdlpftdelrqrycl
    dtwgvwprpdwlltsfwggdlraasniifsngnldpwagggirrnlsasviavtiqggah
    hldlrashpedpasvvearkleatiigewvkaarreqqpalrggprlsl
    

    Sequence, based on observed residues (ATOM records):
    >3n0tA (A:)
    dpgfqerffqqrldhfnferfgnktfpqrflvsdrfwvrgegpiffytgnegdvwafann
    safvaelaaergallvfaehryygkslpfgaqstqrghtelltveqaladfaellralrr
    dlgaqdapaiafggsyggmlsaylrmkyphlvagalaasapvlavaglgdsnqffrdvta
    dfegqspkctqgvreafrqikdlflqgaydtvrwefgtcqplsdekdltqlfmfarnaft
    vlammdypyptdflgplpanpvkvgcdrllseaqritglralaglvynasgsehcydiyr
    lyhscadptgcgtgpdarawdyqacteinltfasnnvtdmfpdlpftdelrqrycldtwg
    vwprpdwlltsfwggdlraasniifsngnldpwagggirrnlsasviavtiqggahhldl
    rashpedpasvvearkleatiigewvkaarre
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3n0tB (B:)
    gamddpgfqerffqqrldhfnferfgnktfpqrflvsdrfwvrgegpiffytgnegdvwa
    fannsafvaelaaergallvfaehryygkslpfgaqstqrghtelltveqaladfaellr
    alrrdlgaqdapaiafggsyggmlsaylrmkyphlvagalaasapvlavaglgdsnqffr
    dvtadfegqspkctqgvreafrqikdlflqgaydtvrwefgtcqplsdekdltqlfmfar
    naftvlammdypyptdflgplpanpvkvgcdrllseaqritglralaglvynasgsehcy
    diyrlyhscadptgcgtgpdarawdyqacteinltfasnnvtdmfpdlpftdelrqrycl
    dtwgvwprpdwlltsfwggdlraasniifsngnldpwagggirrnlsasviavtiqggah
    hldlrashpedpasvvearkleatiigewvkaarreqqpalrggprlsl
    

    Sequence, based on observed residues (ATOM records):
    >3n0tB (B:)
    dpgfqerffqqrldhfnferfgnktfpqrflvsdrfwvrgegpiffytgnegdvwafann
    safvaelaaergallvfaehryygkslpfgaqstqrghtelltveqaladfaellralrr
    dlgaqdapaiafggsyggmlsaylrmkyphlvagalaasapvlavaglgdsnqffrdvta
    dfegqspkctqgvreafrqikdlflqgaydtvrwefgtcqplsdekdltqlfmfarnaft
    vlammdypyptdflgplpanpvkvgcdrllseaqritglralaglvynasgsehcydiyr
    lyhscadptgcgtgpdarawdyqacteinltfasnnvtdmfpdlpftdelrqrycldtwg
    vwprpdwlltsfwggdlraasniifsngnldpwagggirrnlsasviavtiqggahhldl
    rashpedpasvvearkleatiigewvkaarre
    

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3n0tC (C:)
    gamddpgfqerffqqrldhfnferfgnktfpqrflvsdrfwvrgegpiffytgnegdvwa
    fannsafvaelaaergallvfaehryygkslpfgaqstqrghtelltveqaladfaellr
    alrrdlgaqdapaiafggsyggmlsaylrmkyphlvagalaasapvlavaglgdsnqffr
    dvtadfegqspkctqgvreafrqikdlflqgaydtvrwefgtcqplsdekdltqlfmfar
    naftvlammdypyptdflgplpanpvkvgcdrllseaqritglralaglvynasgsehcy
    diyrlyhscadptgcgtgpdarawdyqacteinltfasnnvtdmfpdlpftdelrqrycl
    dtwgvwprpdwlltsfwggdlraasniifsngnldpwagggirrnlsasviavtiqggah
    hldlrashpedpasvvearkleatiigewvkaarreqqpalrggprlsl
    

    Sequence, based on observed residues (ATOM records):
    >3n0tC (C:)
    dpgfqerffqqrldhfnferfgnktfpqrflvsdrfwvrgegpiffytgnegdvwafann
    safvaelaaergallvfaehryygkslpfgaqstqrghtelltveqaladfaellralrr
    dlgaqdapaiafggsyggmlsaylrmkyphlvagalaasapvlavaglgdsnqffrdvta
    dfegqspkctqgvreafrqikdlflqgaydtvrwefgtcqplsdekdltqlfmfarnaft
    vlammdypyptdflgplpanpvkvgcdrllseaqritglralaglvynasgsehcydiyr
    lyhscadptgcgtgpdarawdyqacteinltfasnnvtdmfpdlpftdelrqrycldtwg
    vwprpdwlltsfwggdlraasniifsngnldpwagggirrnlsasviavtiqggahhldl
    rashpedpasvvearkleatiigewvkaarr
    

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3n0tD (D:)
    gamddpgfqerffqqrldhfnferfgnktfpqrflvsdrfwvrgegpiffytgnegdvwa
    fannsafvaelaaergallvfaehryygkslpfgaqstqrghtelltveqaladfaellr
    alrrdlgaqdapaiafggsyggmlsaylrmkyphlvagalaasapvlavaglgdsnqffr
    dvtadfegqspkctqgvreafrqikdlflqgaydtvrwefgtcqplsdekdltqlfmfar
    naftvlammdypyptdflgplpanpvkvgcdrllseaqritglralaglvynasgsehcy
    diyrlyhscadptgcgtgpdarawdyqacteinltfasnnvtdmfpdlpftdelrqrycl
    dtwgvwprpdwlltsfwggdlraasniifsngnldpwagggirrnlsasviavtiqggah
    hldlrashpedpasvvearkleatiigewvkaarreqqpalrggprlsl
    

    Sequence, based on observed residues (ATOM records):
    >3n0tD (D:)
    pgfqerffqqrldhfnferfgnktfpqrflvsdrfwvrgegpiffytgnegdvwafanns
    afvaelaaergallvfaehryygkslpfgaqstqrghtelltveqaladfaellralrrd
    lgaqdapaiafggsyggmlsaylrmkyphlvagalaasapvlavaglgdsnqffrdvtad
    fegqspkctqgvreafrqikdlflqgaydtvrwefgtcqplsdekdltqlfmfarnaftv
    lammdypyptdflgplpanpvkvgcdrllseaqritglralaglvynasgsehcydiyrl
    yhscadptgcgtgpdarawdyqacteinltfasnnvtdmfpdlpftdelrqrycldtwgv
    wprpdwlltsfwggdlraasniifsngnldpwagggirrnlsasviavtiqggahhldlr
    ashpedpasvvearkleatiigewvkaar