PDB entry 3mzw

View 3mzw on RCSB PDB site
Description: her2 extracelluar region with affinity matured 3-helix affibody zher2:342
Deposited on 2010-05-13, released 2010-07-28
The last revision was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine kinase-type cell surface receptor HER2
    Species: Homo sapiens [TaxId:9606]
    Gene: ERBB2, HER2, MLN19, NEU, NGL
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Immunoglobulin G-binding protein A
    Species: STAPHYLOCOCCUS AUREUS, synthetic [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P38507 (Start-57)
      • engineered mutation (8-9)
      • engineered mutation (12-13)
      • engineered mutation (16-17)
      • engineered mutation (23-24)
      • engineered mutation (26-28)
      • engineered mutation (31)
      • engineered mutation (34)
  • Heterogens: NAG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.07, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3mzwA (A:)
    tqvctgtdmklrlpaspethldmlrhlyqgcqvvqgnleltylptnaslsflqdiqevqg
    yvliahnqvrqvplqrlrivrgtqlfednyalavldngdplnnttpvtgaspgglrelql
    rslteilkggvliqrnpqlcyqdtilwkdifhknnqlaltlidtnrsrachpcspmckgs
    rcwgessedcqsltrtvcaggcarckgplptdccheqcaagctgpkhsdclaclhfnhsg
    icelhcpalvtyntdtfesmpnpegrytfgascvtacpynylstdvgsctlvcplhnqev
    taedgtqrcekcskpcarvcyglgmehlrevravtsaniqefagckkifgslaflpesfd
    gdpasntaplqpeqlqvfetleeitgylyisawpdslpdlsvfqnlqvirgrilhngays
    ltlqglgiswlglrslrelgsglalihhnthlcfvhtvpwdqlfrnphqallhtanrped
    ecvgeglachqlcarghcwgpgptqcvncsqflrgqecveecrvlqglpreyvnarhclp
    chpecqpqngsvtcfgpeadqcvacahykdppfcvarcpsgvkpdlsympiwkfpdeega
    cqpcpincthscvdlddkgcpaeq
    

    Sequence, based on observed residues (ATOM records):
    >3mzwA (A:)
    tqvctgtdmklrlpaspethldmlrhlyqgcqvvqgnleltylptnaslsflqdiqevqg
    yvliahnqvrqvplqrlrivrgtqlfednyalavldngdplspgglrelqlrslteilkg
    gvliqrnpqlcyqdtilwkdifhknnqlaltlidtnrsrachpcspmckgsrcwgessed
    cqsltrtvcaggcarckgplptdccheqcaagctgpkhsdclaclhfnhsgicelhcpal
    vtyntdtfesmpnpegrytfgascvtacpynylstdvgsctlvcplhnqevtaedgtqrc
    ekcskpcarvcyglgmehlrevravtsaniqefagckkifgslaflpesfdgdpasntap
    lqpeqlqvfetleeitgylyisawpdslpdlsvfqnlqvirgrilhngaysltlqglgis
    wlglrslrelgsglalihhnthlcfvhtvpwdqlfrnphqallhtanrpedecvgeglac
    hqlcarghcwgpgptqcvncsqflrgqecveecrvlqglpreyvnarhclpchpecqpqn
    gsvtcfgpeadqcvacahykdppfcvarc
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3mzwB (B:)
    vdnkfnkemrnayweiallpnlnnqqkrafirslyddpsqsanllaeakklndaqapk
    

    Sequence, based on observed residues (ATOM records):
    >3mzwB (B:)
    nkemrnayweiallpnlnnqqkrafirslyddpsqsanllaeakklndaqapk