PDB entry 3mxx

View 3mxx on RCSB PDB site
Description: Crystal structure of WDR5 mutant (S62A)
Class: Transcription
Keywords: WDR5, WD-repeat protein 5, Asp-His-Ser-Trp tetrad, Thermostability, circular dichroism, folding energy, guanidine hydrochloride, Transcription
Deposited on 2010-05-08, released 2010-10-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2010-12-01, with a file datestamp of 2010-11-26.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.19
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: WD repeat-containing protein 5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61964 (11-314)
      • expression tag (0-10)
      • engineered mutation (42)
    Domains in SCOPe 2.07: d3mxxa1, d3mxxa2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3mxxA (A:)
ggqqmgrgsefvkpnyalkftlaghtkavssvkfspngewlaassadklikiwgaydgkf
ektisghklgisdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnp
qsnlivsgsfdesvriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwd
tasgqclktlidddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghknek
ycifanfsvtggkwivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasa
alendktiklwksdc