PDB entry 3mxi

View 3mxi on RCSB PDB site
Description: TREX1 3' Exonuclease D18N Familial Chilblain Lupus Mutant
Class: hydrolase/DNA
Keywords: RNase H-like fold, Polyproline type II helix, HYDROLASE-DNA complex
Deposited on 2010-05-07, released 2011-05-18
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-05-18, with a file datestamp of 2011-05-13.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: 0.212
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Three prime repair exonuclease 1
    Species: Mus musculus [TaxId:10090]
    Gene: Trex1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q91XB0
      • engineered mutation (17)
    Domains in SCOPe 2.01: d3mxia_
  • Chain 'B':
    Compound: Three prime repair exonuclease 1
    Species: Mus musculus [TaxId:10090]
    Gene: Trex1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q91XB0
      • engineered mutation (17)
    Domains in SCOPe 2.01: d3mxib_
  • Chain 'C':
    Compound: DNA (5'-d(*gp*ap*cp*g)-3')
  • Chain 'D':
    Compound: DNA (5'-d(*gp*ap*cp*g)-3')
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3mxiA (A:)
    mgsqtlphghmqtliflnleatglpssrpevtelcllavhrralentsisqghpppvprp
    prvvdklslciapgkacspgaseitglskaelevqgrqrfddnlaillraflqrqpqpcc
    lvahngdrydfpllqtelarlstpspldgtfcvdsiaalkaleqasspsgngsrksyslg
    siytrlywqaptdshtaegdvltllsicqwkpqallqwvdeharpfstvkpmygtpattg
    tt
    

    Sequence, based on observed residues (ATOM records): (download)
    >3mxiA (A:)
    tlphghmqtliflnleatglpssrpevtelcllavhrralesqghpppvprpprvvdkls
    lciapgkacspgaseitglskaelevqgrqrfddnlaillraflqrqpqpcclvahngdr
    ydfpllqtelarlstpspldgtfcvdsiaalkaleqasksyslgsiytrlywqaptdsht
    aegdvltllsicqwkpqallqwvdeharpfstvkpmygt
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3mxiB (B:)
    mgsqtlphghmqtliflnleatglpssrpevtelcllavhrralentsisqghpppvprp
    prvvdklslciapgkacspgaseitglskaelevqgrqrfddnlaillraflqrqpqpcc
    lvahngdrydfpllqtelarlstpspldgtfcvdsiaalkaleqasspsgngsrksyslg
    siytrlywqaptdshtaegdvltllsicqwkpqallqwvdeharpfstvkpmygtpattg
    tt
    

    Sequence, based on observed residues (ATOM records): (download)
    >3mxiB (B:)
    lphghmqtliflnleatglpssrpevtelcllavhrraleghpppvprpprvvdklslci
    apgkacspgaseitglskaelevqgrqrfddnlaillraflqrqpqpcclvahngdrydf
    pllqtelarlstpspldgtfcvdsiaalkalesyslgsiytrlywqaptdshtaegdvlt
    llsicqwkpqallqwvdeharpfstvkpmyg
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.