PDB entry 3mvh
View 3mvh on RCSB PDB site
Description: Crystal structure of Akt-1-inhibitor complexes
Class: transferase
Keywords: kinase inhibitor, TRANSFERASE
Deposited on
2010-05-04, released
2010-06-02
The last revision prior to the SCOPe 2.05 freeze date was dated
2011-03-30, with a file datestamp of
2011-03-25.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: 0.181
AEROSPACI score: 0.46
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: v-akt murine thymoma viral oncogene homolog 1 (AKT1)
Species: Homo sapiens [TaxId:9606]
Gene: AKT-1, AKT1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d3mvha_ - Chain 'B':
Compound: GSK3-beta peptide
Database cross-references and differences (RAF-indexed):
- Heterogens: MN, WFE, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3mvhA (A:)
gamdprvtmnefeylkllgkgtfgkvilvkekatgryyamkilkkevivakdevahtlte
nrvlqnsrhpfltalkysfqthdrlcfvmeyanggelffhlsrervfsedrarfygaeiv
saldylhseknvvyrdlklenlmldkdghikitdfglckegikdgatmktfcgtpeylap
evledndygravdwwglgvvmyemmcgrlpfynqdheklfelilmeeirfprtlgpeaks
llsgllkkdpkqrlgggsedakeimqhrffagivwqhvyekklsppfkpqvtsetdtryf
deeftaqmititppdqddsmecvdserrphfpqfdysassta
Sequence, based on observed residues (ATOM records): (download)
>3mvhA (A:)
vtmnefeylkllgkgtfgkvilvkekatgryyamkilkkevivakdevahtltenrvlqn
srhpfltalkysfqthdrlcfvmeyanggelffhlsrervfsedrarfygaeivsaldyl
hseknvvyrdlklenlmldkdghikitdfglckegikdgatmktfcgtpeylapevledn
dygravdwwglgvvmyemmcgrlpfynqdheklfelilmeeirfprtlgpeaksllsgll
kkdpkqrlgggsedakeimqhrffagivwqhvyekklsppfkpqvtsetdtryfdeefta
qrphfpqfdysa
- Chain 'B':
No sequence available.