PDB entry 3msx

View 3msx on RCSB PDB site
Description: Crystal structure of RhoA.GDP.MgF3 in complex with GAP domain of ArhGAP20
Class: protein binding
Keywords: protein-proten complex, transition state, GTPase, PROTEIN BINDING
Deposited on 2010-04-29, released 2011-03-16
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-03-16, with a file datestamp of 2011-03-11.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: 0.196
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: transforming protein rhoa
    Species: Homo sapiens [TaxId:9606]
    Gene: ARH12, ARHA, RHO12, RHOA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61586 (Start-179)
      • engineered (24)
    Domains in SCOPe 2.03: d3msxa_
  • Chain 'B':
    Compound: Rho GTPase-activating protein 20
    Species: Homo sapiens [TaxId:9606]
    Gene: ARHGAP20, KIAA1391
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3msxb_
  • Heterogens: GDP, MG, MGF, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3msxA (A:)
maairkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdt
agqedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkd
lrndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq

    Sequence, based on observed residues (ATOM records): (download) 
    >3msxA (A:)
irkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdtagq
edydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlrn
dehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3msxB (B:)
pssptspmpgqlfgislpnicendnlpkpvldmlfflnqkgpltkgifrqsanvkscrel
keklnsgvevhldcesifviasvlkdflrnipgsifssdlydhwvsvmdqgndeekintv
qrlldqlpranvvllrylfgvlhnieqhsssnqmtafnlavcvapsilwppassspelen
eftkkvslliqflienclrif

    Sequence, based on observed residues (ATOM records): (download) 
    >3msxB (B:)
gqlfgislpnicendnlpkpvldmlfflnqkgpltkgifrqsanvkscrelkeklnsgve
vhldcesifviasvlkdflrnipgsifssdlydhwvsvmdqgndeekintvqrlldqlpr
anvvllrylfgvlhnieqhsssnqmtafnlavcvapsilwppassspeleneftkkvsll
iqflienclrif