PDB entry 3msx

View 3msx on RCSB PDB site
Description: Crystal structure of RhoA.GDP.MgF3 in complex with GAP domain of ArhGAP20
Class: protein binding
Keywords: protein-proten complex, transition state, GTPase, PROTEIN BINDING
Deposited on 2010-04-29, released 2011-03-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: transforming protein rhoa
    Species: Homo sapiens [TaxId:9606]
    Gene: ARH12, ARHA, RHO12, RHOA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61586 (Start-179)
      • engineered (24)
    Domains in SCOPe 2.07: d3msxa_
  • Chain 'B':
    Compound: Rho GTPase-activating protein 20
    Species: Homo sapiens [TaxId:9606]
    Gene: ARHGAP20, KIAA1391
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3msxb_
  • Heterogens: GDP, MG, MGF, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3msxA (A:)
    maairkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdt
    agqedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkd
    lrndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq
    

    Sequence, based on observed residues (ATOM records): (download)
    >3msxA (A:)
    irkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdtagq
    edydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlrn
    dehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3msxB (B:)
    pssptspmpgqlfgislpnicendnlpkpvldmlfflnqkgpltkgifrqsanvkscrel
    keklnsgvevhldcesifviasvlkdflrnipgsifssdlydhwvsvmdqgndeekintv
    qrlldqlpranvvllrylfgvlhnieqhsssnqmtafnlavcvapsilwppassspelen
    eftkkvslliqflienclrif
    

    Sequence, based on observed residues (ATOM records): (download)
    >3msxB (B:)
    gqlfgislpnicendnlpkpvldmlfflnqkgpltkgifrqsanvkscrelkeklnsgve
    vhldcesifviasvlkdflrnipgsifssdlydhwvsvmdqgndeekintvqrlldqlpr
    anvvllrylfgvlhnieqhsssnqmtafnlavcvapsilwppassspeleneftkkvsll
    iqflienclrif