PDB entry 3mrq
View 3mrq on RCSB PDB site
Description: Crystal Structure of MHC class I HLA-A2 molecule complexed with Melan-A MART1 decapeptide variant
Class: immune system
Keywords: MHC class I, HLA, IMMUNE SYSTEM, IMMUNE RESPONSE, DECAPEPTIDE, TUMORAL PEPTIDE, MELAN-A, MART1
Deposited on
2010-04-29, released
2011-05-25
The last revision prior to the SCOPe 2.02 freeze date was dated
2011-05-25, with a file datestamp of
2011-05-20.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.193
AEROSPACI score: 0.39
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: HLA class I histocompatibility antigen, A-2 alpha chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA, HLA-A, HLAA
Database cross-references and differences (RAF-indexed):
- Uniprot P01892 (0-End)
- engineered mutation (244)
- Chain 'B':
Compound: Beta-2-microglobulin
Species: Homo sapiens [TaxId:9606]
Gene: B2M, Beta-2 microglubulin, CDABP0092, HDCMA22P
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d3mrqb_ - Chain 'P':
Compound: 10-meric peptide from Melanoma antigen recognized by T-cells 1
Species: HOMO SAPIENS, synthetic [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q16655 (0-9)
- see remark 999 (1)
- engineered mutation (4)
- engineered mutation (7)
- Heterogens: HOH